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The Value of Programmed Electrical Stimulation in Triggered Activity-Induced Arrhythmias

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Lethal Arrhythmias Resulting from Myocardial Ischemia and Infarction

Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 94))

Abstract

Triggered activity induced by delayed afterdepolarizations has been investigated extensively in tissues isolated from different sites in the heart and from different species. In spite of this we still do not know the clinical relevance of this arrhythmogenic mechanism. An answer to this question is important because the ability to identify mechanisms in the clinical situation can improve our understanding of pathophysiology and provide new treatments. Presently, different methods are used to discriminate among mechanisms of arrhythmias, including electrical stimulation [1], antiarrhythmic drugs, and recording of monophasic action potentials. Unfortunately no method has proven to be sufficiently sensitive or specific [2, 3].

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References

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Authors
  1. Anton P. M. Gorgels
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  2. Marc A. Vos
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  3. Pedro Brugada
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  4. Hein J. J. Wellens
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Editor information

Editors and Affiliations

  1. Department of Pharmacology, Columbia University College of Physicians and Surgeons, 630 West 168th Street, P&S 7-517, New York, 10032, New York, USA

    Michael R. Rosen M.D. (Professor of Pharmacology and Pediatrics) (Professor of Pharmacology and Pediatrics)

  2. Rappaport Family Institute for Research in the Medical Sciences, Technion-Israel Institute of Technology, Efron Street, Post Office Box 9697, Haifa, 31096, Israel

    Yoram Palti M.D., Ph.D. (Director) (Director)

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© 1989 Kluwer Academic Publishers, Boston/Dordrecht/London

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Gorgels, A.P.M., Vos, M.A., Brugada, P., Wellens, H.J.J. (1989). The Value of Programmed Electrical Stimulation in Triggered Activity-Induced Arrhythmias. In: Rosen, M.R., Palti, Y. (eds) Lethal Arrhythmias Resulting from Myocardial Ischemia and Infarction. Developments in Cardiovascular Medicine, vol 94. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1649-7_20

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  • DOI: https://doi.org/10.1007/978-1-4613-1649-7_20

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8916-6

  • Online ISBN: 978-1-4613-1649-7

  • eBook Packages: Springer Book Archive

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