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Central Nervous System Modulation of Cardiac Rhythm

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Book cover Lethal Arrhythmias Resulting from Myocardial Ischemia and Infarction

Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 94))

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Abstract

The conceptual framework of this chapter is based on two fundamental assumptions. The first is that behavioral states are associated with distinct patterns of autonomic nervous system activity. The second is that the resulting neurohumoral profile will determine the intermediary mechanisms responsible for arrhythmias in susceptible individuals. Accordingly, the major modalities for arrhythmogenesis could include direct effects of neurotransmitters on the myocardium and its specialized conducting system and impaired perfusion due to inappropriate coronary vasoconstriction and/or enhanced platelet aggregability (figure 12–1).

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Authors
  1. Richard L. Verrier
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Editors and Affiliations

  1. Department of Pharmacology, Columbia University College of Physicians and Surgeons, 630 West 168th Street, P&S 7-517, New York, 10032, New York, USA

    Michael R. Rosen M.D. (Professor of Pharmacology and Pediatrics) (Professor of Pharmacology and Pediatrics)

  2. Rappaport Family Institute for Research in the Medical Sciences, Technion-Israel Institute of Technology, Efron Street, Post Office Box 9697, Haifa, 31096, Israel

    Yoram Palti M.D., Ph.D. (Director) (Director)

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© 1989 Kluwer Academic Publishers, Boston/Dordrecht/London

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Verrier, R.L. (1989). Central Nervous System Modulation of Cardiac Rhythm. In: Rosen, M.R., Palti, Y. (eds) Lethal Arrhythmias Resulting from Myocardial Ischemia and Infarction. Developments in Cardiovascular Medicine, vol 94. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1649-7_12

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  • DOI: https://doi.org/10.1007/978-1-4613-1649-7_12

  • Publisher Name: Springer, Boston, MA

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