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Receptor Mechanisms in Ischemia and Infarction

  • August M. Watanabe
Part of the Developments in Cardiovascular Medicine book series (DICM, volume 94)

Abstract

The autonomic nervous system, consisting of the sympathetic and parasympathetic limbs, is the most important system extrinsic to the heart for regulating cardiac function. Much has been learned in the last few years about the molecular mechanisms by which the autonomic nervous system regulates the heart. The components of the autonomic nervous system that regulate the heart include sympathetic and vagal nerve terminals, beta-adrenergic and muscarinic receptors, a transmembrane signal transduction system, protein kinases that phosphorylate various proteins within the myocardial cell, and the proteins themselves whose functions are altered when they are phosphorylated [1–6]. For discussion of regulation and interaction at the level of sympathetic and vagal nerves, see the chapter by Levy in this volume.

Keywords

Autonomic Nervous System Adenylate Cyclase Muscarinic Receptor Adenylate Cyclase Activity Positive Inotropic Effect 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Kluwer Academic Publishers, Boston/Dordrecht/London 1989

Authors and Affiliations

  • August M. Watanabe

There are no affiliations available

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