Abstract
Infection of mice or rats with Chilo Iridescent Virus, type 6 (CIV) or Frog Virus 3 (FV 3) produces an acute degenerative hepatitis leading to the death of the animals in less than 24 hr. The integrity of the viral genome is not required for pathogenic expression since solubilized viral proteins exhibit pathogenic properties similar to those of intact virus.
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Aubertin, A. M., Hirth, C., Travo, C., Nonnenmacher, H., and Kirn, A. J. Virol. 11: 694–701, 1973.
Aubertin, A.M., Travo, C., and Kirn, A. J. Virol. 18: 34–41, 1976.
Aubertin, A.M., Anton, M., Bingen, A., Elharrar, M., and Kirn, A. Nature 265: 456–457, 1977.
Bingen-Brendel, A., Batzenschlager, A., Gut, J. P., Hirth, C., Vetter, J.M., and Kirn, A. Ann, Inst. Pasteur 122: 125–142, 1972.
Bingen, A., and Kirn, A. J. Ultrastructure Res. 45: 343–355, 1975.
Bingen, A., and Kirn, A. J. Ultrastructure Res. 50: 167–173, 1975.
Brinton, M.A., and Plagemann, P.G.W. Intervirol. 12: 349–356, 1979.
Cerutti, M., and Devauchelle, G. Arch. Virol. 63: 297–303, 1980.
Cerutti, M., Guerillon, J., Arella, M., and Devau-chelle, G. CR Acad. Sci. Paris 292: 797–802, 1981.
Devauchelle, G., Attias, J., Monnier, C., Barray, S., Cerutti, M., Guerillon, J., and Orange-Balange, N. Current Topics in Microbiology and Immunology 116: 37–48, 1985.
Elharrar, M., Bingen, A., Gendrault, J.L., and Kirn, A. In: Pathogenesis and Mechanisms of Liver Cell Necrosis. MTP Press Ltd, Lancaster, 1975, pp 75–86.
Gendrault, J. L., Steffan, A. M., Bingen, A., and Kirn., A. In: Kupffer Cells and Other Liver Sinusoidal Cells. Elsevier North Holland Biomed. Press, Amsterdam, 1977, pp 223–232.
Granoff, A., Came, P. F., and Breeze, D.C. Virology 29: 133–148, 1966.
Gut, J. P., Anton, M., Bingen, A., Vetter, J. M., and Kirn, A. Lab. Invest. 45: 218–228, 1981.
Gut, J. P., Schmitt, S., Bingen, A., Anton, M., and Kirn, A. J. Infect. Dis. 149: 621–629, 1984.
Hagman, W., Steffan, A. M., Kirn, A., and Keppler, D. Hepatology 7: 732–736, 1987.
Hagman, W., and Keppler, D. In: The Liver: Biology and Pathobiology. Raven Press Ltd., New York, 1988, pp 793–806.
Kief, H., Baehr, H., Deutschlaender, N., and Engel-bart, K. In: Activation of Macrophages. Excerpta Medica, Amsterdam, 1974, pp 31–39.
Kirn, A., Gut, J. P., Bingen, A., and Hirth, C. Arch. ges. Virusforsch. 36: 394–397, 1972.
Kirn, A., Gut, J. P., Steffan, A. M., and Gendrault, J. L. Intervirol. 2: 244–252, 1973/74.
Kirn, A., Gut, J. P., Bingen, A., Steffan, A.M. Hepatology 3: 105–111, 1983.
Knook, D. L., and Sleyster, E. C. Biochem. Biophys. Res. Comm. 96: 250–275, 1980.
Lorbacher de Ruiz, H., Gelderblom, H., Hofmann, W., and Darai, G. Med. Microbiol. Immunol. 175: 43–53, 1986.
Mori, M., and Novikoff, A. B. J. Cell Biol. 72: 695–706, 1977.
Popper, H. In: The Liver: Biology and Pathobiology. Raven Press Ltd., New York, 1988, pp 1087–1103.
Sljivic, V.S. Experientia 25: 1004–1006, 1969.
Steffan, A.M., and Kirn, A. J. Reticuloendothel. Soc. 26: 531–537, 1979.
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© 1990 Kluwer Academic Publishers
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de Ruiz, H.L. (1990). Hepatotoxicity of Iridoviruses. In: Darai, G. (eds) Molecular Biology of Iridoviruses. Developments in Molecular Virology, vol 10. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1615-2_11
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DOI: https://doi.org/10.1007/978-1-4613-1615-2_11
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