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The Role of the Blood Pressure in the Mechanism of Congestive Cardiac Failure

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Pathophysiology and Pharmacology of Heart Disease

Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 102))

Abstract

The Classical theory of backward failure derives from the ideas of Hope (1832). According to the theory an overworked ventricle first hypertrophies. Then, as the load becomes impossible for it to cope with, it dilates and the blood gets dammed up behind it. This increases the pressure in the relevant atrium and the increased pressure is transmitted backwards through the venous system ultimately to the capillary. Here the increased hydrostatic pressure squeezes liquid out of the capillaries into the tissues to form oedema.

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References

  1. Axelrod BJ, Cates JE, Johnson BB, Luetscher JA Jr. Aldosterone in urine of normal man of patients with oedema. Br Med J 1955;i:196–9.

    Google Scholar 

  2. Biron P, Koiw E, Nowaczynski W, Brouillet J, Genest J. Effects of intravenous infusion of valine-5-angiotensin II and other pressor agents on urinary electrolytes and corticosteroids, including aldosterone. J Clin Invest 1961;40:338–47.

    Article  PubMed  CAS  Google Scholar 

  3. de Bold AJ. Heart atria granularity. Effects of changes in water electrolyte balance. Proc Soc Exp Biol Med 1979;161:508–11.

    PubMed  Google Scholar 

  4. Briggs AP, Fowell DM, Hamilton WF, Remington JW, Wheeler NC, Winslow JW. Renal and circulatory factors in the edema formation of congestive heart failure. J Clin Invest 1948;27:810–7.

    Article  CAS  Google Scholar 

  5. Bristow JD, Brown EB Jr, Cunningham DJC, et al. Effects of bicycling on the baroreflex regulation of pulse interval. Circ Res 1971;28:582–92.

    Google Scholar 

  6. Bristow MR, Ginsburg R, Minobe W, et al. Decreased catecholamine sensitivity and beta-adrenergic-receptor density in failing human hearts. N Engl J Med 1982;307:205–11.

    Article  PubMed  CAS  Google Scholar 

  7. Bronk DW, Stella G. Afferent impulses in the carotid sinus nerve. I. The relation of the discharge from single end organs to arterial blood pressure. J Cell Comp Physiol 1932;1:113–30.

    Article  Google Scholar 

  8. Chidsey CA, Braunwald E, Morrow AG. Catecholamine excretion and cardiac stores of norepinephrine in congestive heart failure. Am J Med 1965; 39:442–51.

    Article  PubMed  CAS  Google Scholar 

  9. Chidsey CA, Harrison DC, Braunwald E. The augmentation of plasma norepinephrine response to exercise in patients with congestive heart failure. N Engl J Med 1962;267:650–4.

    Article  PubMed  CAS  Google Scholar 

  10. Chidsey CA, Kaister GA, Sonnenblick EH, Spann JF, Braunwald E. Cardiac norepinephrine stores in experimental heart failure in the dog. J Clin Invest 1964;43:2386–93.

    Article  PubMed  CAS  Google Scholar 

  11. Chidsey CA, Sonnenblick EH, Morrow AG, Braunwald E. Norepinephrine stores and contractile force of papillary muscle from the failing heart. Circulation 1966;33:43–51.

    PubMed  CAS  Google Scholar 

  12. Covell JW, Chidsey CA, Braunwald E. Reduction of the cardiac response to postganglionic sympathetic nerve stimulation in experimental heart failure. Circ Res 1966;19:51–6.

    Google Scholar 

  13. Dietz JR. Release of natriuretic factor from rat heart-lung preparations by atrial distension. Am J Physiol 1984;247:R1093–6.

    PubMed  CAS  Google Scholar 

  14. Eckberg DL, Drabinsky M, Braunwald E. Defective cardiac parasympathetic control in patients with heart disease. N Engl J Med 1971;285:877–83.

    Article  PubMed  CAS  Google Scholar 

  15. Eckberg DL, Fletcher GF, Braunwald E. Influence of background autonomic activity upon the response to carotid sinus nerve stimulation in man (Abstract). Am J Cardiol 1970;26:631.

    Article  Google Scholar 

  16. Fahr G, Ershler I. Studies of factors concerned in edema formation. II. The hydrostatic pressure in the capillaries during edema formation in right heart failure. Ann Intern Med 1941;15:798–810.

    CAS  Google Scholar 

  17. Greenberg TT, Richmond WH, Stocking RA, Gupta PD, Meehan JP, Henry JP. Impaired atrial receptor responses in dogs with heart failure due to tricuspid insufficiency and pulmonary artery stenosis. Circ Res 1973;32:424–33.

    PubMed  CAS  Google Scholar 

  18. Hamilton WF, Richards DW. The output of the heart. In: Fishman AP, Richards DW, eds. Circulation of the blood. Men and ideas. New York: Oxford University Press, 1965:71–126.

    Google Scholar 

  19. Higgins CB, Vatner SF, Eckberg DL, Braunwald E. Alterations in the baroreceptor reflex in conscious dogs with heart failure. J Clin Invest 1972;51:715–24.

    Article  PubMed  CAS  Google Scholar 

  20. Hökfelt T, Fuxe K, Goldstein M, Johansson O. Immunohistochemical evidence for the existence of adrenaline neurons in the rat brain. Brain Res 1974;66:235–51.

    Article  Google Scholar 

  21. Hope J. A treatise on the disease of the heart and great vessels, and on the affections which may be taken for them: comprising the author’s view of the physiology of the heart’s action and sounds. London: John Churchill, 1832.

    Google Scholar 

  22. Mackenzie J. Disease of the heart. 3rd ed. Oxford Medical Publications, 1913:26.

    Google Scholar 

  23. Merrill AJ. Edema and decreased renal blood flow in patients with chronic congestive heart failure: evidence of “forward failure” as primary cause of edema. J Clin Invest 1946;25:389–400.

    Article  Google Scholar 

  24. Mokotoff R, Ross G, Leiter I. Renal plasma flow and sodium reabsorption and excretion in congestive heart failure. J Clin Invest 1948;27:1–9.

    Article  CAS  Google Scholar 

  25. Ross CA, Armstrong DM, Ruggiero DA, Pickel VM, Joh TH, Reis DJ. Adrenaline neurons in the rostral ventrolateral medulla innervate thoracic spinal cord. Neurosci Lett 1981;25:257–62.

    Article  PubMed  CAS  Google Scholar 

  26. Sarnoff SJ, Berglund E. Ventricular function. I. Starling’s law of the heart studied by means of simultaneous right and left ventricular curves. Circulation 1954;9:706–18.

    PubMed  Google Scholar 

  27. Starling EH. On the absorption of fluids from the connective tissue spaces. J Physiol 1896;19:312–26.

    PubMed  CAS  Google Scholar 

  28. Starling EH. The Unacre lecture on the law of the heart given at Cambridge, 1915. London: Longmans, Green, 1918.

    Google Scholar 

  29. Starr I. Role of the “static blood pressure” in abnormal increments of venous pressure, especially in heart failure. II. Clinical and experimental studies. Am J Med Sci 1940;199:40–55.

    Article  Google Scholar 

  30. Starr I, Rawson AJ. Role of the “static blood pressure” in abnormal increments of venous pressure, especially in heart failure. I. Theoretical studies on an improved circulation scheme whose pumps obey Starling’s law of the heart. Am J Med Sc 1940;199:27–39.

    Article  Google Scholar 

  31. Wade OL, Bishop JM. Cardiac output and regional blood flow. Oxford: Blackwell, 1962.

    Google Scholar 

  32. Warren JV, Stead EA Jr. Fluid dynamics in chronic congestive failure. Arch Intern Med 1944;73:138–47.

    Google Scholar 

  33. Watkins L Jr, Burton JA, Haber E, Cant JR, Smith FW, Barger AC. The renin-aldosterone system in congestive failure on conscious dogs. J Clin Invest 1976;57:1606–17.

    Article  PubMed  CAS  Google Scholar 

  34. Wollheim E. Die Zirkulierende blutmenge und ihre bedeutung fur kompensation und dekompensation des kreislaufs. Z Klin Med 1931;116:269–397.

    Google Scholar 

  35. Wood PW. Disease of the heart and circulation. Philadelphia: Lippincott, 1956.

    Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Cardiac Medicine, The Cardiothoracic Institute, Dovehouse Street, London, SW3 6LY, UK

    P. Harris

Authors
  1. P. Harris
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Editor information

Editors and Affiliations

  1. Postgraduate Institute of Medical Education & Research, Chandigarh, India

    Inder S. Anand  & Purshotam L. Wahi  & 

  2. St. Boniface General Hospital Research Center, Winnipeg, Canada

    Naranjan S. Dhalla

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© 1989 Kluwer Academic Publishers

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Harris, P. (1989). The Role of the Blood Pressure in the Mechanism of Congestive Cardiac Failure. In: Anand, I.S., Wahi, P.L., Dhalla, N.S. (eds) Pathophysiology and Pharmacology of Heart Disease. Developments in Cardiovascular Medicine, vol 102. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1607-7_12

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  • DOI: https://doi.org/10.1007/978-1-4613-1607-7_12

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8889-3

  • Online ISBN: 978-1-4613-1607-7

  • eBook Packages: Springer Book Archive

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