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Myocardial Reperfusion: Role of Adjunctive Agents to Improve Reperfusion and Prevent Reperfusion Injury

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Risk/Benefit Analysis for the Use and Approval of Thrombolytic, Antiarrhythmic, and Hypolipidemic Agents

Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 100))

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Abstract

Thrombolysis with intravenous streptokinase, APSAC and tissue plasminogen activator has been shown to improve ventricular function and survival in patients with acute myocardial infarction (1–4). Despite these important advances several problems remain and we may not have achieved the optimal benefit from reperfusion therapy.

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Author information

Authors and Affiliations

  1. Division of Cardiology, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, MI, USA

    B. Pitt & B. Lucchesi

  2. Department of Pharmacology, University of Michigan Medical Center, Ann Arbor, MI, USA

    B. Pitt & B. Lucchesi

Authors
  1. B. Pitt
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  2. B. Lucchesi
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Editor information

Editors and Affiliations

  1. Likoff Cardiovascular Institute of Hahnemann Medical College and Hospital, USA

    Joel Morganroth

  2. School of Veterinary Medicine, University of Pennsylvania, USA

    E. Neil Moore

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© 1989 Kluwer Academic Publishers

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Pitt, B., Lucchesi, B. (1989). Myocardial Reperfusion: Role of Adjunctive Agents to Improve Reperfusion and Prevent Reperfusion Injury. In: Morganroth, J., Moore, E.N. (eds) Risk/Benefit Analysis for the Use and Approval of Thrombolytic, Antiarrhythmic, and Hypolipidemic Agents. Developments in Cardiovascular Medicine, vol 100. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1605-3_5

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  • DOI: https://doi.org/10.1007/978-1-4613-1605-3_5

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8888-6

  • Online ISBN: 978-1-4613-1605-3

  • eBook Packages: Springer Book Archive

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