Abstract
Despite intensive clinical research efforts of the past 15 years, little real progress has been made in the management of lung cancer, and the outlook for patients whose tumors cannot be completely resected remains grim. Obviously, the surgical and radiotherapeutic treatment modalities are approaching the limits of their potential efficacies, and the early promise of combination chemotherapy has only partially been realized. New cytotoxic agents with significant activity in lung cancer are difficult to find, and the results of early clinical trials with biological agents such as the interferons or interleukins raise little hope of major activity.
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Rodenhuis, S. (1989). Oncogenes and Human Lung Cancer. In: Hansen, H.H. (eds) Basic and Clinical Concepts of Lung Cancer. Cancer Treatment and Research, vol 45. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1593-3_6
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DOI: https://doi.org/10.1007/978-1-4613-1593-3_6
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