Abstract
The hydrophobic effect has been a topic of chemical interest for more than a century. This phenomenon, in its most general terms, is concerned with the solubility of molecules in water and in nonpolar solvents (Tanford, 1980). Liquid water dissolves polar substances readily but nonpolar substances only sparingly. On mixing, water “squeezes out” hydrophobic molecules, resulting in a separation into polar and nonpolar phases. The spontaneous segregation of oil after mixing with water serves as a familiar example.
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© 1989 Plenum Press, New York
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Rose, G.D., Dworkin, J.E. (1989). The Hydrophobicity Profile. In: Fasman, G.D. (eds) Prediction of Protein Structure and the Principles of Protein Conformation. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1571-1_15
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DOI: https://doi.org/10.1007/978-1-4613-1571-1_15
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