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CMV Infections and Immune Responses

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Herpesviruses, the Immune System, and AIDS

Part of the book series: Developments in Medical Virology ((DIMV,volume 6))

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Abstract

CMV is an important pathogen in immunocompromised persons, including neonates, AIDS patients, organ transplant patients and oncology patients. Immunologic studies in humans and mice indicate a critical role for cytotoxic lymphocytes in recovery from infection. Cytotoxic T cell responses to products of the immediate early genes may be particularly important and these findings may provide a basis for the development of effective vaccines and for strategies to adoptively transfer immunity to CMV.

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Author information

Authors and Affiliations

  1. Oncology Center, The Johns Hopkins University School of Medicine, Baltimore, Maryland, 21205, USA

    W. H. Burns

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  1. W. H. Burns
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Editors and Affiliations

  1. The University of Maryland, Baltimore, USA

    Laure Aurelian M.D.

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© 1990 Kluwer Academic Publishers

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Burns, W.H. (1990). CMV Infections and Immune Responses. In: Aurelian, L. (eds) Herpesviruses, the Immune System, and AIDS. Developments in Medical Virology, vol 6. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1507-0_5

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  • DOI: https://doi.org/10.1007/978-1-4613-1507-0_5

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8810-7

  • Online ISBN: 978-1-4613-1507-0

  • eBook Packages: Springer Book Archive

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