Abstract
Clinical trials performed during the past three decades have provided valuable data regarding the effects of antihypertensive drug therapy on the development of cardiovascular complications. The data differ somewhat according to the degree of severity of hypertension, and the findings in patients with moderate and severe hypertension (diastolic blood pressures 105–114 mmHg and ≥ 115 mmHg, respectively) should best be considered separately from those in patients with mild hypertension (diastolic pressures 90–104 mmHg).
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© 1990 Kluwer Academic Publishers
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Chobanian, A.V. (1990). What Have We Learned from Prior Clinical Trials of Antihypertensive Drug Therapy?. In: Morganroth, J., Moore, E.N. (eds) Use and Approval of Antihypertensive Agents and Surrogate Endpoints for the Approval of Drugs Affecting Antiarrhythmic Heart Failure and Hypolipidemia. Developments in Cardiovascular Medicine, vol 112. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1505-6_7
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DOI: https://doi.org/10.1007/978-1-4613-1505-6_7
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4612-8809-1
Online ISBN: 978-1-4613-1505-6
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