Abstract
With increasingly aggressive multimodality treatment, the ability to cure or at least obtain long-term survival for significant numbers of children with primary or secondary brain tumors is becoming more commonplace, with further success on the horizon. With this increasing survival rate comes the responsibility to evaluate closely the subtle and more overt long-term effects on the children themselves—not only physical and functional effects, but behavioral, neuropsychological, and intellectual effects as well. Long-term physical and hormonal effects are easily evaluated and quantitated, and early intervention may modify the long-term effects on the child. Other long-term sequelae, however, are less easily defined and can require a comprehensive range of tests to even establish a general area of deficiency, let alone to determine the cause and effect mechanisms.
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Silverman, C.L., Thomas, P.R.M. (1990). Long-term Neuropsychologic and Intellectual Sequelae in Brain Tumor Patients. In: Deutsch, M. (eds) Management of Childhood Brain Tumors. Foundations of Neurological Surgery, vol 3. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1501-8_23
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DOI: https://doi.org/10.1007/978-1-4613-1501-8_23
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