Abstract
For the first half of this century, success in the treatment of childhood brain tumors often was measured just in terms of six-month survival rates. The high operative mortality associated with brain tumor surgery contributed to the overall dismal results. The lack of accurate noninvasive imaging techniques in the years prior to the development of computerized tomography (CT) precluded the accurate localization of many tumor types and also the early diagnosis of tumor and hydrocephalus. In addition, the limitations of orthovoltage radiation equipment precluded the administration of homogeneous high doses of radiation to the craniospinal axis and even to localized areas of the brain except with the best of techniques. The occasional long-term survivor usually had a biologically nonaggressive tumor. Keith et al. traced 256 children treated for intracranial tumor between 1920 and 1944 [1].
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Deutsch, M. (1990). Late Sequelae in Survivors of Childhood Brain Tumors. In: Deutsch, M. (eds) Management of Childhood Brain Tumors. Foundations of Neurological Surgery, vol 3. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1501-8_22
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DOI: https://doi.org/10.1007/978-1-4613-1501-8_22
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