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Parasitic Diseases

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Controlled Clinical Trials in Neurological Disease

Part of the book series: Foundations of Neurology ((FONY,volume 1))

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Abstract

Parasitic diseases of the nervous system constitute one of the most important causes of death and disability in tropical countries. Of particular importance for tropical neurology are cerebral malaria, neurocysticercosis, and schistosomiasis. Outside of the tropics, opportunistic infection with the intracellular protozoan Toxoplasma gondii has become a common neurological complication of the acquired immunodeficiency syndrome (AIDS) [1,2]. Other parasitic diseases of the nervous system [3] include African and American trypanosomiasis, amoebiasis, paragonimiasis and other trematode infections, eosinophilic meningitis, gnathostomiasis, trichinosis, hydatid cyst, and other tapeworm diseases, including neurological complications resulting from vitamin B12 deficiency induced by intestinal parasitism with the tapeworm of cold-water fishes, Diphyllobothrium latum. Also common is the invasion of the human nervous system by migrating larvae of intestinal parasites of dogs (Toxocara canis), cats (Toxocara cati), and men (Strongyloides stercoralis) or by ectoparasite larvae, such as in myasis produced by bot flies (Dermatobia hominis, Oestrus ovis). “River blindness,” resulting from ophthalmic involvement by the filarial nematode Onchocerca volvulus, is one of the most common causes of blindness in Africa, Central America and South America. Eye lesions and occasional lesions of the nervous system are also seen with other filarial parasites such as Loa loa, Dracunculus medinensis, and Dirofilaria immitis.

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Authors
  1. Gustavo C. Román
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Editors and Affiliations

  1. National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA

    Roger J. Porter  & Bruce S. Schoenberg  & 

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© 1990 Kluwer Academic Publishers

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Román, G.C. (1990). Parasitic Diseases. In: Porter, R.J., Schoenberg, B.S. (eds) Controlled Clinical Trials in Neurological Disease. Foundations of Neurology, vol 1. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1495-0_25

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  • DOI: https://doi.org/10.1007/978-1-4613-1495-0_25

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8804-6

  • Online ISBN: 978-1-4613-1495-0

  • eBook Packages: Springer Book Archive

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