Abstract
Atherosclerosis produces variable arterial wall thickening from cholesterol deposition, cellular infiltration and proliferation, fibrosis, calcification, and, eventually necrosis. This process results in progressive diminution of coronary arterial lumen size and blood flow. Conventional diagnostic methods do not completely characterize the atherosclerotic process in human arteries. Contrast coronary angiography is the most commonly used diagnostic method to assess anatomy and is routinely used to make critical decisions about patient treatment and prognosis. Angiography provides a two-dimensional image of lumen contour only, but gives no information about either the volume or composition of the atheroma present [1–3]. Details of disrupted coronary anatomy following coronary angioplasty, including dissections, flaps of tissue, and false lumens, can be difficult to discern from contrast angiograms.
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Mallery, J.A., Tobis, J.M., Gessert, J.M., Griffith, J.M., Berns, M.W., Henry, W.L. (1990). Intravascular Ultrasound Imaging. In: Abela, G.S. (eds) Lasers in Cardiovascular Medicine and Surgery: Fundamentals and Techniques. Developments in Cardiovascular Medicine, vol 103. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1489-9_31
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DOI: https://doi.org/10.1007/978-1-4613-1489-9_31
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