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The ultrastructure of bone tumors

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Part of the Electron Microscopy in Biology and Medicine book series (EMBM, volume 7)

Abstract

The approach to the diagnosis of bone tumors is generally based on the radiographic appearance and the pathology of these lesions, and adequate biopsy of the tumor with histologic examination of the tissue under the light microscope is usually satisfactory in most cases. However, due to morphologic similarities or lack of differentiation, certain tumors present a problem of diagnosis or classification to the pathologist. It is in these instances where modern diagnostic techniques such as immunohistochemistry and electron microscopy play an important role. Electron microscopy, which is widely used in diagnostic pathology, has also extended into the field of bone pathology. At the present time there are a substantial number of articles dealing with the ultrastructure of bone tumors, most of which were published within the last 15 years. Several extensive reports in this subject are already available in the literature [1–4].

Keywords

Rough Endoplasmic Reticulum Fibrous Dysplasia Malignant Fibrous Histiocytoma Giant Cell Tumor Osteoid Osteoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Kluwer Academic Publishers 1990

Authors and Affiliations

  1. 1.Department of Pathology and Laboratory Medicine Hospital for Joint DiseasesOrthopaedic InstituteNew YorkUSA

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