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The insulin receptor

  • Chapter
Understanding Insulin Action

Part of the book series: Ellis Horwood Series in Biochemistry and Biotechnology ((EMISS))

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Abstract

Many hormones and other extracellular stimuli exert their effects by binding to specific receptors on the plasma membrane of cells. The receptors recognize and bind the agonists with high affinity, and are therefore responsible for initiating the cascade of reactions leading to intracellular events. The hormone-receptor complex transmits this signal in various ways which are the subject of the next chapter, but which include interaction with a guanine-nucleotide-binding protein, activation of an effector enzyme, and generation of second messengers.

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Authors and Affiliations

  1. Department of Endocrinology, Glaxo Research Laboratories, Research Triangle Park, North Carolina, USA

    J. Espinal B.Sc., D.Phil (Head of Diabetes Research Section)

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  1. J. Espinal B.Sc., D.Phil
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© 1989 J. Espinal/Ellis Horwood Limited

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Espinal, J. (1989). The insulin receptor. In: Understanding Insulin Action. Ellis Horwood Series in Biochemistry and Biotechnology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1475-2_5

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  • DOI: https://doi.org/10.1007/978-1-4613-1475-2_5

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8794-0

  • Online ISBN: 978-1-4613-1475-2

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