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Advances in screening for colorectal cancer

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Advances in Cancer Screening

Part of the book series: Cancer Treatment and Research ((CTAR,volume 86))

Abstract

There are relatively few established etiologic factors for colorectal cancer, and therefore primary prevention remains speculative. Diet has been most widely studied, and results indicate that diets high in fat, meat, and protein are positively associated with colorectal cancer, whereas diets high in vegetables, fruits, and fibers are negatively associated [1]. Intervention studies have yet to show that modifying diets will alter risk.

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References

  1. Potter JD, Slattery ML, Bostick RM, Gapstur SM. 1993. Colon cancer: A review of the literature. Epidemiol Rev 15: 499–545.

    PubMed  CAS  Google Scholar 

  2. Mandel JS, Bond JH, Church TR, Snover DC, Bradley GM, Schuman LM, Ederer F. 1993. Reducing mortality from colorectal cancer by screening for fecal occult blood. N Engl J Med 328: 1365–1371.

    Article  PubMed  CAS  Google Scholar 

  3. Greegor DH. 1967. Diagnosis of large-bowel cancer in the asymptomatic patient. JAMA 201: 943–945.

    Article  PubMed  CAS  Google Scholar 

  4. Winawer SJ. 1993. Colorectal cancer screening comes of age. N Engl J Med 328: 1416–1417.

    Article  PubMed  CAS  Google Scholar 

  5. Gilbertson VA, Church TR, Greive FJ, Mandel JS, McHugh RB, Schuman LM, Williams SE. 1980. The design of a study to assess occult blood screening for colon cancer. J Chron Dis 33: 107–114.

    Article  Google Scholar 

  6. Lang CA, Ransohoff D. 1994. Fecal occult blood screening for colorectal cancer. JAMA 271: 1011–1013.

    Article  PubMed  CAS  Google Scholar 

  7. Ederer F, Church TR, Mandel JS. Submitted. Fecal occult blood screening: does chance detection of nonbleeding cancers really play an important role in preventing death from colorectal cancer?

    Google Scholar 

  8. Kewenter J, Björk S, Haglind E, Smith L, Svanik J, Ahren C. 1988. Screening and rescreening for colorectal cancer. Cancer 62: 645–651.

    Article  PubMed  CAS  Google Scholar 

  9. Kewenter J, Asztely M, Engaras B, Haglund E, Smith L, Svanvik J, Ahern C. 1991. A randomized trial of faecal occult blood testing for early detection of colorectal cancer: results of screening and rescreening of 51,325 subjects. In Miller AB, Chamberlain J, Day NE, Hakama M, Prorok PC (eds.), Cancer Screening. Cambridge, England: Cambridge University Press, pp. 117–125.

    Google Scholar 

  10. Kewenter J, Brevinge H, Engaras B, Haglind E, Ahren C. 1994. Follow-up after screening for colorectal neoplasms with fecal occult blood testing in a controlled trial. Dis Colon Rectum 37: 115–119.

    Article  PubMed  CAS  Google Scholar 

  11. Kewenter J, Brevinge H, Engaras B, Hagind E, Ahren C. 1994. Results of screening, rescreening and followup in a prospective randomized study for detection of colorectal cancer by fecal occult blood testing. Results for 68,308 subjects. Scand J Gastroenterol 29: 468–473.

    Article  PubMed  CAS  Google Scholar 

  12. Hardcastle JD, Ferrands PA, Balfour TW, Chamberlain J, Amar SS, Sheldon MG. 1983. Controlled trial of faecal occult blood testing in the detection of colorectal cancer. Lancet ii: 1–4.

    Article  Google Scholar 

  13. Hardcastle JD, Armitage NC, Chamberlain J, Amar SS, James PD, Balfour TW. 1986. Fecal occult blood screening for colorectal cancer in the general population. Results of a controlled trial. Cancer 58: 397–403.

    Article  PubMed  CAS  Google Scholar 

  14. Hardcastle JD, Thomas WM, Chamberlain J, Pye G, Sheffield J, James PD, Balfour TW, Amar SS, Armitage NC, Moss SM. 1989. Randomised, controlled trial of faecal occult blood screening for colorectal cancer: results for first 107,349 subjects. Lancet i: 1160–1164.

    Article  Google Scholar 

  15. Hardcastle JD. 1991. Randomized control trial of faecal occult blood screening for colorectal cancer: results for the first 144,103 patients. Eur J Cancer Prev 1: 21.

    Article  PubMed  Google Scholar 

  16. Thomas WM, Hardcastle JD. 1991. An update on the Nottingham trial of fecal occult blood screening for colorectal cancer. In Miller AB, Chamberlain J, Day NE, Hakama M, Prorok PC (eds.), Cancer Screening. Cambridge, England: Cambridge University Press, pp. 106–115.

    Google Scholar 

  17. Klaaborg K, Madsen MS, Sondergaard O, Kronborg O.1986. Participation in mass screening for colorectal cancer with fecal occult blood test. Scand J Gastroenterol 21: 1180–1184.

    Article  PubMed  CAS  Google Scholar 

  18. Krönborg O, Fenger C, Sondergaard O, Pederson KM, Olsen J. 1987. Initial mass screening for colorectal cancer with fecal occult blood test: a prospective randomized study at Funen in Denmark. Scand J Gastroenterol 22: 677–686.

    Article  PubMed  Google Scholar 

  19. Krönborg O, Fenger C, Olsen J, Bech K, Sondergaard O. 1989. Repeated screening for colorectal cancer with fecal occult blood test: a prospective randomized study at Funen, Denmark. Scand J Gastroenterol 24: 599–606.

    Article  PubMed  Google Scholar 

  20. Krönborg O, Fenger C, Worm J, Pedersen SA, Hem J, Bertelson K, Olsen J. 1992. Causes of death during the first 5 years of a randomized trial of mass screening for colorectal cancer with fecal occult blood test. Scand J Gastroenterol 27: 47–52.

    Article  PubMed  Google Scholar 

  21. Jensen BM, Krönborg O, Fenger C. 1992. Interval cancers in screening with fecal occult blood test for colorectal cancer. Scand J Gastroenterol 27: 779–782.

    Article  PubMed  CAS  Google Scholar 

  22. Krönborg O, Fenger C. 1994. A randomized population trial with Hemoccult II for colorectal cancer (abstract). World Congress for Gastroenterology, Los Angeles.

    Google Scholar 

  23. Faivre J, Arveaux P, Milan C, Durand G, Lamour J, Bedenne L. 1991. Participation in mass screening for colorectal cancer: results of screening and rescreening from the Burgundy study. Eur J Cancer Prev 1: 49–55.

    Article  PubMed  CAS  Google Scholar 

  24. Arveux P, Durand G, Milan C, Bedenne L, Levy D, Doan BOH, Faivre J. 1992. Views of a general population on mass screening of colorectal cancer: the Burgundy study. Prev Med 21: 574–581.

    Article  PubMed  CAS  Google Scholar 

  25. Winawer SJ, Schottenfeld D, Flehinger BJ. 1991. Colorectal cancer screening. J Natl Cancer Inst 83: 243–253.

    Article  PubMed  CAS  Google Scholar 

  26. Winawer SJ, Flehinger BJ, Schottenfeld D, Miller DG. 1993. Screening for colorectal cancer with fecal occult blood testing and sigmoidoscopy. J Natl Cancer Inst 85: 1311–1318.

    Article  PubMed  CAS  Google Scholar 

  27. Selby JV, Friedman GD, Quesenberry CP, Weiss NS. 1993. Effects of fecal occult blood testing on mortality from colorectal cancer. A case-control study. Ann Intern Med 118: 1–6.

    PubMed  CAS  Google Scholar 

  28. Wahrendorf J, Robra BP, Wiebelt H, Oberhausen R, Weiland M, Dhom G. 1993. Effectiveness of colorectal cancer screening: results from a population-based case-control evaluation in Saarland, Germany. Eur J Cancer Prev 2: 221–227.

    Article  PubMed  CAS  Google Scholar 

  29. Newcomb PA, Norfleet RG, Storer BE, Surawicz TS, Marcus PM. 1992. Screening sigmoidoscopy and colorectal cancer mortality. J Natl Cancer Inst 84: 1572–1575.

    Article  PubMed  CAS  Google Scholar 

  30. Lazovich D, Weiss NS, Stevens NG, White E, McKnight B, Wagner EH. 1995. A case- control study to evaluate efficacy of screening for fecal occult blood. J Med Screening 2: 84–89.

    CAS  Google Scholar 

  31. St. John DJB. 1990. Faecal occult blood tests: a critical review. In Hardcastle JD (ed.), Screening for Colorectal Cancer. Englewood, NJ: Normed Verlag, pp. 55–68.

    Google Scholar 

  32. Songster CL, Barrows GH, Jarrett DD. 1980. Immunochemical detection of fecal occult blood. The fecal smear punch-disc test: a new non-invasive screening test for colorectal cancer. Cancer 45: 1099–1102.

    Article  PubMed  CAS  Google Scholar 

  33. Turunen MJ, Liewendahl K, Partanen P, Adlercreutz H. 1984. Immunological detection of faecal occult blood in colorectal cancer. Br J Cancer 49: 141–148.

    Article  PubMed  CAS  Google Scholar 

  34. Armitage N, Hardcastle JD, Amar SS, Balfour TW, Haynes J, James PD. 1985. A comparison of an immunological faecal occult blood test Fecatwin sensitive/FECA EIA with Haemoccult in population screening for colorectal cancer. Br J Cancer 51: 799–804.

    Article  PubMed  CAS  Google Scholar 

  35. St. John DBJ, Young GP, Alexeyeff FM, Deacon M, Cuthbertson AM. 1990. Most large and medium colorectal adenomas can be detected by immuno-chemical occult blood tests. Gastroenterology 98: A312.

    Google Scholar 

  36. Castiglione G, Grazzini G, Ciatto S. 1992. Guaiac and immunochemical tests for faecal occult blood in colorectal cancer screening. Br J Cancer 65: 942–944.

    Article  PubMed  CAS  Google Scholar 

  37. Thomas WM, Hardcastle JD, Jackson J, Pye G. 1992. Chemical and immunological testing for fecal occult blood: a comparison of two tests in symptomatic patients. Br J Cancer 65: 618–620.

    Article  PubMed  CAS  Google Scholar 

  38. St. John DJB, Young GP, Alexeyeff MA, Deacon MC, Cuthbertson AM, Macrae FA, Penfold JCB. 1993. Evaluation of new occult blood tests for detection of colorectal neoplasia. Gastroenterology 104: 1661–1668.

    PubMed  CAS  Google Scholar 

  39. Robinson MHE, Marks CG, Farrands PA, Thomas WM, Hardcastle JD. 1994. Population screening for colorectal cancer: a comparison between guaiac and immunological fecal occult blood tests. Br J Surg 81: 448–451.

    Article  PubMed  CAS  Google Scholar 

  40. Oshima A. 1994. A critical review of cancer screening programs in Japan. Int J Technol Assess Health Care 10: 3, 346–358.

    Article  Google Scholar 

  41. Saito H, Soma Y, Koeda J, Wada T, Kawaguchi H, Sobue T, Aisawa T, Yoshida Y. 1995. Reduction in risk of mortality from colorectal cancer by fecal occult blood screening with immunochemical hemagglutination test. A case-control study. Int J Cancer 61: 465–469.

    Article  PubMed  CAS  Google Scholar 

  42. Petrelli N, Michalek AM, Freedman A, Baroni M, Mink I, Rodriguez-Bigas M. 1994. Immunochemical versus guaiac occult blood stool tests: results of a community-based screening program. Surg Oncol 3: 27–36.

    Article  PubMed  CAS  Google Scholar 

  43. Castiglione G, Sala P, Ciatto S, Grazzini G, Mazzotta A, Rossetti C, Spinelli P, Bertario L. 1994. Comparative analysis of results of guaiac and immunochemical tests for faecal occult blood in colorectal cancer screening in two oncological institutions. Eur J Cancer Prev 3: 399–405.

    Article  PubMed  CAS  Google Scholar 

  44. Schwartz S, Dahl J, Ellefson M, Ahlquist D. 1983. The “HemoQuant” test: A specific and quantitative determination of heme (hemoglobin) in feces and other materials. Clin Chem 29: 2061–2067.

    PubMed  CAS  Google Scholar 

  45. Schwartz S, Ellefson M. 1983. Fecal recovery of hemoproteins from blood, meat, and fish ingested by normal volunteers: the HemoQuant assay. Gastroenterology 84: 1302.

    Google Scholar 

  46. Ahlquist DA, McGill DB, Schwartz S, Taylor WF, Owen RA. 1985. Fecal blood levels in health and disease. A study using HemoQuant. N Engl J Med 312: 1422–1428.

    Article  PubMed  CAS  Google Scholar 

  47. St. John DJB, Young GP, McHutchison JG, Deacon MC, Alexeyeff MA. 1992. Comparison of the specificity and sensitivity of Hemoccult and HemoQuant in screening for colorectal neoplasia. Ann Intern Med 117: 376–382.

    PubMed  CAS  Google Scholar 

  48. Ahlquist DA, Wieand HS, Moertel CG, McGill DB, Loprinzi CL, O’Connell MJ, Mailliard JA, Gerstner JB, Pandya K, Ellefson RD. 1993. Accuracy of fecal occult blood screening for colorectal neoplasia. A prospective study of Hemoccult and HemoQuant tests. JAMA 269: 1262–1267.

    Article  PubMed  CAS  Google Scholar 

  49. Young GP, St. John DJB. 1991. Selecting an occult blood test for use as a screening tool for large bowel cancer. In Rozen P, Reich CB, Winawer SJ (eds.), Large Bowel Cancer: Policy, Prevention, Research and Treatment. Frontiers of Gastrointestinal Research, vol. 18. Basel: Karger, pp. 135–156.

    Google Scholar 

  50. Young GP, Rose IS, St. John DJB. 1989. Haem in the gut. I. Fate of haemoproteins and the absorption of haem. J Gastroenterol Hepatol 4: 537–545.

    Article  PubMed  CAS  Google Scholar 

  51. Young GP, St. John DJB, Rose IS, Blake D. 1990. Haem in the gut. Part II. Faecal excretion of haem and haem-derived porphyrins and their detection. J Gastroenterol Hepatol 5: 194–203.

    Article  PubMed  CAS  Google Scholar 

  52. Herzog P, Holtermuller KH, Preiss J, Fischer J, Ewe K, Schreiber HJ, Berres M. 1982. Fecal blood loss in patients with colonic polyps: a comparison of measurements with chromium- labeled erythrocytes and with the Haemoccult test. Gastroenterology 83: 957–962.

    PubMed  CAS  Google Scholar 

  53. Griffith CDM, Turner DJ, Saunders JH. 1981. False negative results of Hemoccult tests in colorectal cancer. Br Med J 283: 472.

    Article  CAS  Google Scholar 

  54. Crowley ML, Freeman LD, Mottet MD, et al. 1983. Sensitivity of guaiac-impregnated cards for the detection of colorectal neoplasia. J Clin Gastroenterol 5: 127–130.

    Article  PubMed  CAS  Google Scholar 

  55. Rosenfield RE, Kochwa S, Kaczera Z, Maimon J. 1979. Nonuniform distribution of occult blood in feces. Am J Clin Pathol 71: 204–209.

    PubMed  CAS  Google Scholar 

  56. Doran J, Hardcastle JD. 1982. Bleeding pattern in colorectal cancer: the effect of aspirin and the implications for faecal occult blood testing. Br J Surg 69: 711–713.

    Article  PubMed  CAS  Google Scholar 

  57. Farrands PA, Hardcastle JD. 1983. Accuracy of occult blood tests over a six-day period. Clin Oncol 9: 217–225.

    PubMed  CAS  Google Scholar 

  58. Macrae FA, St. John DJB. 1982. Relationship between patterns of bleeding and Hemoccult sensitivity in patients with colorectal cancers or adenomas. Gastroenterology 82: 891–898.

    PubMed  CAS  Google Scholar 

  59. Ahlquist DA, McGill DB, Fleming JL, Schwartz S, Wieand HS, Rubin J, Moertel CG. 1989. Patterns of occult bleeding in asymptomatic colorectal cancer. Cancer 63: 1826–1830.

    Article  PubMed  CAS  Google Scholar 

  60. Ahlquist DA, Klee GG, McGill DB, Ellefson RD. 1990. Colorectal cancer detection in the practice setting. Impact of fecal occult blood testing. Arch Intern Med 150: 1041–1045.

    Article  PubMed  CAS  Google Scholar 

  61. Macrae FA, St. John DJB, Caligiore P, Taylor LS, Legge JW. 1982. Optimal dietary conditions for Hemoccult testing. Gastroenterology 82: 899–903.

    PubMed  CAS  Google Scholar 

  62. Simon JB. 1985. Occult blood screening for colorectal carcinoma: a critical review. Gastroenterology 88: 820–837.

    PubMed  CAS  Google Scholar 

  63. Simon JB. 1987. The pros and cons of fecal occult blood testing for colorectal neoplasms. Cancer Metastasis Rev 6: 397–411.

    Article  PubMed  CAS  Google Scholar 

  64. Winawer SJ, Zauber A, Diaz B. 1987. The National Polyp Study: temporal sequence of evolving colorectal cancer from the normal colon. Gastrointest Endoscop 33: 167.

    Google Scholar 

  65. Bertario L, Spinelli P, Gennari L, Sala P, Pizzetti P, Severini A, Cozzi G, Bellomi M, Berrino F. 1988. Sensitivity of Hemoccult test for large bowel cancer in high-risk subjects. Dig Dis Sci 33: 609–613.

    Article  PubMed  CAS  Google Scholar 

  66. Mandel JS, Bond JH, Bradley M, Snover DC, Church TR, Williams S, Watt G, Schuman LM, Ederer F, Gilbertsen V. 1989. Sensitivity, specificity and positive predictivity of the Hemoccult test in screening for colorectal cancers. Gastroenterology 97: 597–600.

    PubMed  CAS  Google Scholar 

  67. Castiglione G, Grazzini G, Poli G, Bonardi R, Ciatto S. 1991. Hemoccult sensitivity estimate in a screening program for colorectal cancer in the Province of Florence. Tumori 77: 243–245.

    PubMed  CAS  Google Scholar 

  68. Moran A, Husband D, Jones AF, Asquith P. 1995. Diagnostic value of a guaiac occult blood test and fecal alpha 1-antitrypsin. Gut 36: 87–89.

    Article  PubMed  CAS  Google Scholar 

  69. Demers RY, Stawick LE, Demers P. 1985. Relative sensitivity of the fecal occult blood test and flexible sigmoidoscopy in detecting polyps. Prev Med 14: 55–62.

    Article  PubMed  CAS  Google Scholar 

  70. Jahn H, Jorgensen OD, Kronborg O, Fenger C. 1992. Can Hemoccult II replace colonoscopy in surveillance after radical surgery for colorectal cancer and after polypectomy? Dis Colon Rectum 35: 253–256.

    Article  PubMed  CAS  Google Scholar 

  71. Winawer SJ, Zauber AG, O’Brien MJ, Gottlieb LS, Sternberg SS, Stewart ET, Bond JH, Schapiro M, Panish JF, Waye JD, Kurtz RC, Shike M, Ho MN, and The National Polyp Study Workgroup. 1992. The National Polyp Study. Design, methods, and characteristics of patients with newly diagnosed polyps. Cancer 70: 1236–1245.

    Article  PubMed  CAS  Google Scholar 

  72. Winawer SJ, Zauber AG, Ho MN, O’Brien MJ, Gottlieb LS, Sternberg SS, Waye JD, Schapiro M, Bond JH, Panish JF, Ackroyd F, Shike M, Kurtz RC, Hornsby-Lewis L, Gerdes H, Stewart ET, and The National Polyp Study workgroup. 1993. Prevention of colorectal cancer by colonoscopic polypectomy. N Engl J Med 329: 1977–1981.

    Article  PubMed  CAS  Google Scholar 

  73. Windeler J, Kobberling J. 1987. Colorectal carcinoma and Haemoccult. A study of its value in mass screening using meta-analysis. Int J Colorect Dis 2: 223–228.

    Article  CAS  Google Scholar 

  74. Illingworth DG. 1965. Influence of diet on occult blood tests. Gut 6: 595–598.

    Article  PubMed  CAS  Google Scholar 

  75. Shapiro S. 1992. Case-control studies of colorectal cancer mortality: is the case made for screening sigmoidoscopy? J Natl Cancer Inst 84: 1546–1547.

    Article  PubMed  CAS  Google Scholar 

  76. Ransohoff DF, Lang CA. 1993. Sigmoidoscopy screening in the 1990’s. JAMA 269: 1278–1281.

    Article  PubMed  CAS  Google Scholar 

  77. Lieberman D. 1994. Colon cancer screening: beyond efficacy. Gastroenterology 106: 803–812.

    PubMed  CAS  Google Scholar 

  78. Lieberman D. 1994. Screening/early detection model for colorectal cancer. Why screen? Cancer 74: 2023–2027.

    Article  PubMed  CAS  Google Scholar 

  79. Morson BC. 1974. The polyp-cancer sequence in the large bowel. Proc R Soc Med 67: 451–457.

    PubMed  CAS  Google Scholar 

  80. Jackman RJ, Mayo CW. 1951. The adenoma-carcinoma sequence in cancer of the colon. Surg Gynecol Obstet 93: 327–330.

    PubMed  CAS  Google Scholar 

  81. Muto T, Bussey HJR, Morson BC. 1975. The evolution of cancer of the colon and rectum. Cancer 36: 2251–2270.

    Article  PubMed  CAS  Google Scholar 

  82. Hill MJ, Morson BC, Bussey HJB. 1978. Aetiology of adenoma-carcinoma sequence on the large bowel. Lancet i: 245–247.

    Article  Google Scholar 

  83. Winawer SJ, O’Brien MJ, Waye JD, Kronborg O, Bond J, Fruhmorgen P, Sobin LH, Burt R, Zauber A, Morson B, and the WHO Collaborating Centre for the Prevention of Colorectal Cancer. 1990. Risk and surveillance of individuals with colorectal polyps. Bull WHO 68: 789–795.

    PubMed  CAS  Google Scholar 

  84. Bronner MP, Haggitt RC. 1993. The polyp-cancer sequence. Do all cancers arise from benign adenomas? In Sivak MV (ed.), Gastrointestinal Endoscopy. Clinics of North America, vol. 3. Philadelphia: W.B. Saunders Co., pp. 611–622.

    Google Scholar 

  85. Dukes CE. 1925. Simple tumors of the large intestine and their relationship to cancer. Br J Surg 13: 720.

    Article  Google Scholar 

  86. Jass JR. 1989. Do all colorectal carcinomas arise in preexisting adenomas? World J Surg 13: 45–51.

    Article  PubMed  CAS  Google Scholar 

  87. Lev R. 1990. Adenomatous Polyps of the Colon. Pathobiological and Clinical Features. New York: Springer-Verlag.

    Book  Google Scholar 

  88. Tierney RP, Ballantyne GH, Modlin IM. 1990. The adenoma to carcinoma sequence. Surg Gynecol Obstet 171: 81–94.

    PubMed  CAS  Google Scholar 

  89. Williams CB, Bedenne L. 1990. Management of colorectal polyps: is all the effort worthwhile? J Gastroenterol Hepatol 1 (Suppl): 144–165.

    Article  Google Scholar 

  90. Eide TJ. 1990. Natural history of adenomas. World J Surg 15: 3–6.

    Article  Google Scholar 

  91. Itzkowitz SH. 1992. The adenomatous polyp. Semin Gastrointestinal Dis 3: 3–12.

    Google Scholar 

  92. Neugut AI, Jacobson JS, DeVivo I. 1993. Epidemiology of colorectal adenomatous polyps. Cancer Epidemiol Biomarkers Prev 2: 159–176.

    PubMed  CAS  Google Scholar 

  93. Grinnell RS, Lane N. 1958. Benign and malignant adenomatous polyps and papillary adenomas of the colon and rectum: an analysis of 1856 tumors in 1335 patients. Int Abstr Surg 106: 519–538.

    PubMed  CAS  Google Scholar 

  94. Morson BC. 1974. Evolution of cancer of the colon and rectum. Cancer 34: 845–849.

    Article  PubMed  Google Scholar 

  95. Fung CHK, Goldman H. 1970. The incidence and significance of villous changes in adenomatous polyps. Am J Clin Pathol 53: 21–25.

    PubMed  CAS  Google Scholar 

  96. Armitage NCM. 1991. Intervention studies in adenoma patients. World J Surg 15: 29–34.

    Article  PubMed  CAS  Google Scholar 

  97. Hoff G, Vatn MH. 1991. Colonic adenoma: natural history. Dig Dis 9: 61–69.

    Article  PubMed  CAS  Google Scholar 

  98. Atkin WS, Morson BC, Cuzick J. 1992. Long-term risk of colorectal cancer after excision of rectosigmoid adenomas. N Engl J Med 326: 658–662.

    Article  PubMed  CAS  Google Scholar 

  99. Vogelstein B, Fearon ER, Hamilton SR, Kern SE, Preisinger AC, Leppert M, Nakamura Y, White R, Smits AMM, Bos JL. 1988. Genetic alterations during colorectal-tumor development. N Engl J Med 319: 525–532.

    Article  PubMed  CAS  Google Scholar 

  100. Kuramoto S, Oohara T. 1988. Minute cancers arising de novo in the human large intestine. Cancer 61: 829–834.

    Article  PubMed  CAS  Google Scholar 

  101. Shimoda T, Ikegami M, Fujisaki J, Matsui T, Aizawa S, Ishikawa E. 1989. Early colorectal carcinoma with special reference to its development de novo. Cancer 64: 1138–1146.

    Article  PubMed  CAS  Google Scholar 

  102. Bedenne L, Faivre J, Boutron MC, Piard F, Cauvin JM, Hillon P. 1992. Adenoma-carcinoma sequence or “de novo” carcinogenesis? A study of adenomatous remnants in a populationbased series of large bowel cancers. Cancer 69: 883–888.

    Article  PubMed  CAS  Google Scholar 

  103. Kuramoto S, Oohara T. 1995. How do colorectal cancers develop? Cancer 75: 1534–1538.

    Article  PubMed  CAS  Google Scholar 

  104. Wolff WI, Shinya H. 1973. Polypectomy via the fiberoptic colonoscope: removal of neoplasms beyond the reach of the sigmoidoscope. N Engl J Med 288: 329–332.

    Article  PubMed  CAS  Google Scholar 

  105. Kozuka S, Nogaki M, Ozeki T, Masumori S. 1975. Premalignancy of the mucosal polyp in the large intestine. II. Estimation of the periods required for malignant transformation of mucosal polyps. Dis Colon Rectum 18: 494–500.

    Article  PubMed  CAS  Google Scholar 

  106. Helwig EB. 1947. The evolution of adenomas of the large intestine and their relation to carcinoma. Surg Gynecol Obstet 84: 36–49.

    PubMed  CAS  Google Scholar 

  107. Correa P, Strong JP, Reif A, Johnson WD. 1977. The epidemiology of colorectal polyps. Prevalence in New Orleans and international comparisons. Cancer 39: 2258–2264.

    Article  PubMed  CAS  Google Scholar 

  108. Blatt LJ. 1961. Polyps of the colon and rectum: incidence and distribution. Dis Colon Rectum 4: 277–282.

    Article  Google Scholar 

  109. Offerhaus GJA, Giardiello FM, Tersmette KWF, Mulder GWR, Tersmette AC, Moore GW, Hamilton SR. 1991. Ethnic differences in the anatomic location of colorectal adenomatous polyps. Int J Cancer 49: 641–644.

    Article  PubMed  CAS  Google Scholar 

  110. Arminski TC, McLean DW. 1964. Incidence and distribution of adenomatous polyps of the colon and rectum based on 1000 autopsy examinations. Dis Colon Rectum 7: 249–261.

    Article  PubMed  CAS  Google Scholar 

  111. Stemmerman GN, Yatani R. 1973. Diverticulosis and polyps of the large intestine: a necropsy study of Hawaiian Japanese. Cancer 31: 1260–1270.

    Article  Google Scholar 

  112. Eide TJ, Stalsberg H. 1978. Polyps of the large intestine in Norther Norway. Cancer 42: 2839–2848.

    Article  PubMed  CAS  Google Scholar 

  113. Vatn MH, Stalsberg H. 1982. The prevalence of polyps of the large intestine in Oslo: an autopsy study. Cancer 49: 819–825.

    Article  PubMed  CAS  Google Scholar 

  114. Williams AR, Balasovriya BAW, Day DW. 1982. Polyps and cancer of the large bowel: a necropsy study in Liverpood. Gut 23: 835–842.

    Article  PubMed  CAS  Google Scholar 

  115. Coode PE, Chan KW, Chan YT. 1985. Polyps and diverticula of the large intestine: a necropsy survey in Hong Kong. Gut 26: 1045–1048.

    Article  PubMed  CAS  Google Scholar 

  116. Bremmer CG, Ackerman LV. 1970. Polyps and carcinoma of the large bowel in the South African Bantu. Cancer 26: 991–999.

    Article  Google Scholar 

  117. Correa P, Duque E, Cuello C, Haenszel W. 1972. Polyps of the colon and rectum in Cali, Columbia. Int J Cancer 9: 86–96.

    Article  PubMed  CAS  Google Scholar 

  118. Cajucom CC, Barrios GC, Gruz L, Varin C, Herrera L. 1992. Prevalence of colorectal polyps in Filipinos. An autopsy study. Dis Colon Rectum 35: 676–680.

    Article  PubMed  CAS  Google Scholar 

  119. Eide TJ. 1986. The age-, sex-, and site-specific occurrence of adenomas and carcinomas of the large intestine within a defined population. Scand J Gastroenterol 21: 1083–1088.

    Article  PubMed  CAS  Google Scholar 

  120. Johannsen LGK, Momsen O, Jacobsen NO. 1989. Polyps of the large intestine in Aarhus, Denmark. An autopsy study. Scand J Gastroenterol 24: 799–806.

    Article  PubMed  CAS  Google Scholar 

  121. Rickert RR, Auerbach O, Garfinkel L, Hammond EC, Frasca JM. 1979. Adenomatous lesions of the large bowel. An autopsy survey. Cancer 43: 1847–1857.

    Article  PubMed  CAS  Google Scholar 

  122. Eide TJ. 1983. Remnants of adenomas in colorectal carcinomas. Cancer 51: 1866–1872.

    Article  PubMed  CAS  Google Scholar 

  123. DeJong WW, Day NE, Muir CS, Barclay THC, Bras G, Foster FH, Jussawalla DJ, Kurihara M, Linden G, Martinez I, Payne PM, Pederson E, Ringertz N, Shanmugaratnum T. 1972. The distribution of cancer within the large bowel. Int J Cancer 10: 463–477.

    Article  CAS  Google Scholar 

  124. Clark JC, Collan Y, Eide TJ, Esteve J, Ewen S, Gibbs NM, Jensen OM, Koskela E, McLennan R, Simpson JG, Stalsberg H, Zaridze DG. 1985. Prevalence of polyps in an autopsy series from areas with varying incidence of large bowel cancer. Int J Cancer 36: 179–186.

    Article  PubMed  CAS  Google Scholar 

  125. Rider JA, Kirsner JB, Moeller HC, Palmer WL. 1954. Polyps of the colon and rectum. Their incidence and relationship to carcinoma. Am J Med 16: 555–564.

    Article  PubMed  CAS  Google Scholar 

  126. Shinya H, Wolff WI. 1979. Morphology, anatomic distribution and cancer potential of colonic polyps. An analysis of 7000 polyps endoscopically removed. Ann Surg 190: 679–683.

    Article  PubMed  CAS  Google Scholar 

  127. Meltzer SJ, Ahnen DJ, Battifora H, Yokota J, Cline MJ. 1987. Protooncogene abnormalities in colon cancers and adenomatous polyps. Gastroenterology 92: 1174–1180.

    PubMed  CAS  Google Scholar 

  128. Fearon ER, Vogelstein B. 1990. A genetic model for colorectal tumorigenesis. Cell 61: 759–767.

    Article  PubMed  CAS  Google Scholar 

  129. Baker SJ, Preisinger AC, Jessup JM, Paraskeva C, Markowitz S, Willson JKV, Hamilton S, Vogelstein B. 1990. p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis. Cancer Res 50: 7717–7722.

    PubMed  CAS  Google Scholar 

  130. Bonnelli U, Martines H, Conio M, Bruzzi P, Aste H. 1986. Family history of colorectal cancer as a risk factor for benign and malignant tumors of the large bowel: a case-control study. Int J Cancer 41: 513–517.

    Google Scholar 

  131. Guillem JG, Forde KA, Treat MR, Neugut AI, O’Toole KM, Diamond BE. 1992. Colonoscopic screening for neoplasms in asymptomatic first-degree relatives of colon cancer patients. Dis Colon Rectum 35: 523–529.

    Article  PubMed  CAS  Google Scholar 

  132. Burt RW, Bishop DT, Cannon LA, Dowdle MA, Lee RG, Skolnick MH. 1985. Dominant inheritance of adenomatous colonic polyps and colorectal cancer. N Engl J Med 312: 1540–1544.

    Article  PubMed  CAS  Google Scholar 

  133. Cannon-Albright LA, Skolnick MH, Bishop DT, Lee RG, Burt RW. 1988. Common inheritance of susceptibility to colonic adenomatous polyps and associated colorectal cancers. N Engl J Med 319: 533–537.

    Article  PubMed  CAS  Google Scholar 

  134. McConnell JC, Nizin JS, Slade MS. 1990. Colonoscopy in patients with a primary family history of colon cancer. Dis Colon Rectum 33: 105–107.

    Article  PubMed  CAS  Google Scholar 

  135. Sauer J, Hoff G, Hausken T, Bjorkheim A, Foerster A, Mowinckel P. 1992. Colonoscopic screening examination of relatives of patients with colorectal cancer. Scand J Gastroenterol 27: 667–672.

    Article  Google Scholar 

  136. Orrom WJ, Brzezinski WS, Wiens EW. 1990. Heredity and colorectal cancer. A prospective community based, endoscopic study. Dis Colon Rectum 33: 490–493.

    Article  PubMed  CAS  Google Scholar 

  137. Gryska PV, Cohen AM. 1987. Screening asymptomatic patients at high risk for colon cancer with full colonoscopy. Dis Colon Rectum 30: 18–20.

    Article  PubMed  CAS  Google Scholar 

  138. Grossman S, Milos ML. 1988. Colonoscopic screening of persons with suspected risk factors for colon cancer. Gastroenterol 94: 395–400.

    CAS  Google Scholar 

  139. Carpenter S, Broughton M, Marks CG. 1995. A screening clinic for relatives of patients with colorectal cancer in a district general hospital. Gut 36: 90–92.

    Article  PubMed  CAS  Google Scholar 

  140. Gaglia P, Atkins WS, Whitelaw S, Talbot IC, Williams CB, Northover JMA, Hodgson SV. 1995. Variables associated with the risk of colorectal adenomas in asymptomatic patients with a family history of colorectal cancer. Gut 36: 385–390.

    Article  PubMed  CAS  Google Scholar 

  141. Neugut AI, Jacobsen JS, Ahsan H, Santos J, Garbowski GC, Forde KA, Treat MR, Waye J. 1995. Incidence and recurrence rates of colorectal adenomas: a prospective study. Gastroenterol 108: 402–408.

    Article  CAS  Google Scholar 

  142. Cannon-Albright LA, Bishop DT, Samowitz W, DiSario JA, Lee R, Burt RW. 1994. Colonic polyps in an unselected population: prevalence, characteristics and associations. Am J Gastroenterol 89: 827–831.

    PubMed  CAS  Google Scholar 

  143. Eide TJ. 1986. Risk of colorectal cancer in adenoma-bearing individuals within a defined population. Int J Cancer 38: 173–176.

    Article  PubMed  CAS  Google Scholar 

  144. Henry LG, Condon RE, Schulte WJ, Aprahamian C, DeCossee JJ. 1975. Risk of recurrent colon polyps. Ann Surg 182: 511–515.

    Article  PubMed  CAS  Google Scholar 

  145. Winawer SJ. 1991. Follow-up after polypectomy. World J Surg 15: 25–28.

    Article  PubMed  CAS  Google Scholar 

  146. Morson BC. 1984. The evolution of colorectal carcinoma. Clin Radiol 35: 425–431.

    Article  PubMed  CAS  Google Scholar 

  147. Neugut AI, Johnsen CM, Forde KA, Treat MR. 1985. Recurrence rates for colorectal polyps. Cancer 55: 1586–1589.

    Article  PubMed  CAS  Google Scholar 

  148. Kronborg O, Fenger C. 1987. Prognostic evaluation of planned follow-up of patients with colorectal adenomas. Int J Colorect Dis 2: 203–207.

    Article  CAS  Google Scholar 

  149. Jorgensen OD, Krönborg O, Fenger C. 1993. The Funen Adenoma Follow-up Study. Characteristics of patients and initial adenomas in relation to severe dysplasia. Scand J Gastroenterol 28: 239–243.

    Article  PubMed  CAS  Google Scholar 

  150. Eddy DM. 1990. Screening for colorectal cancer. Ann Intern Med 113: 373–384.

    PubMed  CAS  Google Scholar 

  151. Connor RJ, Prorok PA, Weed DL. 1991. The case-control design and the assessment of the efficacy of cancer screening. J Clin Epidemiol 44: 1215–1221.

    Article  PubMed  CAS  Google Scholar 

  152. Weiss NS, McKnight B, Stevens NG. 1992. Approaches to the analysis of case-control studies of the efficacy of cancer screening. Am J Epidemiol 135: 817–823.

    PubMed  CAS  Google Scholar 

  153. Moss SM. 1991. Case-control studies of screening. Int J Cancer 20: 1–6.

    CAS  Google Scholar 

  154. Atkin WS, Cuzick J, Northover JMA, Whynes DK. 1993. Prevention of cancer by once-only sigmoidoscopy. Lancet 341: 736–740.

    Article  PubMed  CAS  Google Scholar 

  155. Gilbertsen VA. 1974. Proctosigmoidoscopy and polypectomy in reducing the incidence of rectal cancer. Cancer 34: 936–939.

    Article  PubMed  Google Scholar 

  156. Gilbertsen VA, Nelms MJ. 1978. The prevention of invasive cancer of the rectum. Cancer 41: 1137–1139.

    Article  PubMed  CAS  Google Scholar 

  157. Miller AB. 1988. Review of sigmoidoscopy screening for colorectal cancer. In Chamberlain J, Miller AB (eds.), Screening for Gastrointestinal Cancer. Toronto: Hans Huber, pp. 3–7.

    Google Scholar 

  158. Cutler JL, Ramcharon S, Feldman R, Siegelaub AB, Campbell BA, Friedman GD, Dales LG, Collens MF. 1973. Multiphasic checkup evaluation study I. Methods. Prev Med 2: 197–206.

    Article  PubMed  CAS  Google Scholar 

  159. Dales LG, Friedman GD, Ramcharon S, Siegelaub AB, Campbell BA, Feldman R, Collen MF. 1973. Multiphasic checkup evaluation study. Outpatient clinic utilization, hospitalization and mortality experience after seven years. Prev Med 2: 221–235.

    Article  PubMed  CAS  Google Scholar 

  160. Friedman GD, Collen MF, Fireman BH. 1986. Multiphasic health checkup evaluation: a 16- year follow-up. J Chron Dis 39: 453–463.

    Article  PubMed  CAS  Google Scholar 

  161. Selby JV, Friedman GD, Collen MF. 1988. Sigmoidoscopy and mortality from colorectal cancer: The Kaiser Permanente Multiphasic Evaluation Study. J Clin Epidemiol 41: 427–434.

    Article  PubMed  CAS  Google Scholar 

  162. Selby JV, Friedman GD, Quesenberry CP, Weiss NS. 1992. A case-control study of screening sigmoidoscopy and mortality from colorectal cancer. N Engl J Med 326: 653–657.

    Article  PubMed  CAS  Google Scholar 

  163. Chapman I. 1963. Adenomatous polypi of large intestine. Incidence and distribution. Ann Surg 157: 223–226.

    Article  PubMed  CAS  Google Scholar 

  164. Sato E, Ouchi A, Sasano N, Ishidate T. 1976. Polyps and diverticulosis of large bowel in autopsy population of Akita prefecture compared with Miyagi. High risk for colorectal cancer in Japan. Cancer 37: 1316–1321.

    Article  PubMed  CAS  Google Scholar 

  165. Bombi JA. 1988. Polyps of the colon in Barcelona, Spain. An autopsy study. Cancer 66: 1472–1476.

    Article  Google Scholar 

  166. Cooper GS, Yuan Z, Landefeld S, Johanson JF, Rimm AA. 1995. A national population- based study of incidence of colorectal cancer and age. Implications for screening in older Americans. Cancer 75: 775–781.

    Article  PubMed  CAS  Google Scholar 

  167. Lieberman D. 1993. Screening colonoscopy. Has the time come? In Swak MV (ed.), Gastrointestinal Endoscopy Clinics of America. Philadelphia: WB Saunders vol. 3: 673–682.

    Google Scholar 

  168. Rogge JD, Elmore MF, Mahoney SJ, Brown ED, Troiano FP, Wagner DR, Black DJ, Pound DC. 1994. Low-cost, office-based screening colonoscopy. Am J Gastroenterol 89: 1775–1780.

    PubMed  CAS  Google Scholar 

  169. Blackburn GL, Giardiello FM. 1995. Developing strategies for intervention/prevention trials of individuals at risk of hereditary colon cancer. Natl Cancer Inst Monogr 17: 107–110.

    Google Scholar 

  170. Tahara E. 1995. Genetic alterations in human gastrointestinal cancers. The application to molecular diagnosis. Cancer 75: 1410–1417.

    Article  PubMed  CAS  Google Scholar 

  171. Blum HE. 1995. Colorectal cancer: future population screening for early colorectal cancer. Eur J Cancer 31A: 1369–1372.

    Article  PubMed  CAS  Google Scholar 

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  1. Jack S. Mandel
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    Anthony B. Miller

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© 1996 Kluwer Academic Publishers

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Mandel, J.S. (1996). Advances in screening for colorectal cancer. In: Miller, A.B. (eds) Advances in Cancer Screening. Cancer Treatment and Research, vol 86. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1265-9_5

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  • DOI: https://doi.org/10.1007/978-1-4613-1265-9_5

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