Cell motility in breast cancer

  • Jason D. Kantor
  • Bruce R. Zetter
Part of the Cancer Treatment and Research book series (CTAR, volume 83)


Tumor growth and metastasis involve a complex interaction between tumor and nontumor cells, characterized by alterations in the regulation of cell behavior. The earliest stage of tumor formation is proliferation. Through genetic mutations, a cell or group of cells becomes refractory to normal growth regulation. The resultant mass of cells exerts pressure on surrounding tissue but does not cross tissue boundaries. Noninvasive tumors have been termed benign and can often be easily removed. The progression from a benign to a malignant tumor entails a series of steps involving both tumor cells and the surrounding tissue.


Hepatocyte Growth Factor Breast Tumor Cell Human Breast Tumor Nucleoside Diphosphate Kinase Fetal Fibroblast 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Kluwer Academic Publishers 1996

Authors and Affiliations

  • Jason D. Kantor
  • Bruce R. Zetter

There are no affiliations available

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