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Cell motility in breast cancer

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Book cover Mammary Tumor Cell Cycle, Differentiation, and Metastasis

Part of the book series: Cancer Treatment and Research ((CTAR,volume 83))

Abstract

Tumor growth and metastasis involve a complex interaction between tumor and nontumor cells, characterized by alterations in the regulation of cell behavior. The earliest stage of tumor formation is proliferation. Through genetic mutations, a cell or group of cells becomes refractory to normal growth regulation. The resultant mass of cells exerts pressure on surrounding tissue but does not cross tissue boundaries. Noninvasive tumors have been termed benign and can often be easily removed. The progression from a benign to a malignant tumor entails a series of steps involving both tumor cells and the surrounding tissue.

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Authors
  1. Jason D. Kantor
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  2. Bruce R. Zetter
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Editors and Affiliations

  1. Departments of Cell Biology and Pharmacology, Lombardi Cancer Center, The Research Building, 3970 Reservoir Road, 20007, Washington, DC, USA

    Robert B. Dickson PHD

  2. Departments of Medicine and Pharmacology, Lombardi Cancer Center, The Research Building, 20007, 3970 Reservoir Road, Washington, CD, USA

    Marc E. Lippman MD

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© 1996 Kluwer Academic Publishers

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Kantor, J.D., Zetter, B.R. (1996). Cell motility in breast cancer. In: Dickson, R.B., Lippman, M.E. (eds) Mammary Tumor Cell Cycle, Differentiation, and Metastasis. Cancer Treatment and Research, vol 83. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1259-8_15

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  • DOI: https://doi.org/10.1007/978-1-4613-1259-8_15

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8536-6

  • Online ISBN: 978-1-4613-1259-8

  • eBook Packages: Springer Book Archive

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