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The Molecular Basis for the Control of Mammalian Cell Growth

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Basic and Clinical Applications of Flow Cytometry

Part of the book series: Developments in Oncology ((DION,volume 77))

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Abstract

Multicellular organisms face a unique problem in regulating proliferation of their component cells. This is because, whereas failure of even a large proportion of cells to divide within a tissue will generally be of little consequence as there are always other cells present that can renew the affected tissue, the unrestrained proliferation of even one cell and its progeny will be lethal. Indeed, this is the disease we call cancer. Recently, there have been many spectacular advances in our understanding of the molecular processes that regulate cell proliferation. This review will outline our current understanding of the major features of cell growth regulation in mammalian cells.

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Authors
  1. Gerard I. Evan
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Editors and Affiliations

  1. Division of Hematology and Oncology, School of Medicine, Wayne State University, 02188, Detroit, Michigan, 48201, USA

    Frederick A. Valeriote Ph.D. , Alexander Nakeff Ph.D.  & Manuel Valdivieso M.D. ,  & 

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© 1996 Kluwer Academic Publishers

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Evan, G.I. (1996). The Molecular Basis for the Control of Mammalian Cell Growth. In: Valeriote, F.A., Nakeff, A., Valdivieso, M. (eds) Basic and Clinical Applications of Flow Cytometry. Developments in Oncology, vol 77. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1253-6_17

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  • DOI: https://doi.org/10.1007/978-1-4613-1253-6_17

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8534-2

  • Online ISBN: 978-1-4613-1253-6

  • eBook Packages: Springer Book Archive

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