Abstract
The power of flow cytometry is evidenced by its ability to measure a variety of parameters on a cell-by-cell basis. The utility of flow cytometric measurements of these parameters becomes evident when it is understood that, for a population of cells, the distribution of these parameters can be determined. Thus, the heterogeneity within cell populations can be determined. This obviates the need for the assumption that an average value obtained for a population of cells (as obtained using a bulk analysis) is representative for each cell within that population.
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Roederer, M., Herzenberg, L.A. (1996). Probing Immune Responses: The Role of Intracellular Glutathione. In: Valeriote, F.A., Nakeff, A., Valdivieso, M. (eds) Basic and Clinical Applications of Flow Cytometry. Developments in Oncology, vol 77. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1253-6_13
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DOI: https://doi.org/10.1007/978-1-4613-1253-6_13
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