Intravascular device-related infections in cancer patients

  • Issam I. Raad
  • Giuseppe Fraschini
Part of the Cancer Treatment and Research book series (CTAR, volume 79)

Abstract

The successful management of oncology patients entails the safe use of intravascular catheters. Central venous catheters (CVC), particularly long-term silastic catheters, are commonly used in cancer patients to administer chemotherapy, antibiotics, blood products, and parenteral nutrition. Infection is one of the leading complications of these devices, and catheter-related septicemias represent the most frequent life-threatening complication of intravascular catheters [1–7]. The rate of septicemias associated with noncuffed CVC has ranged from 4 percent to 14 percent [8]. For long-term cuffed silastic catheters, a range of 8–43 percent has been reported [5]. More than 5 million CVCs are inserted in the United States annually [9]. Of those, about 0.5 million are cuffed silastic catheters [10]. Assuming a conservative average septicemia rate of only 8 percent, one would expect at least 400,000 CVC-related septicemias per year.

Keywords

Thrombin Polyurethane Laminin Osteomyelitis Aminoglycosides 

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Copyright information

© Kluwer Academic Publishers 1995

Authors and Affiliations

  • Issam I. Raad
  • Giuseppe Fraschini

There are no affiliations available

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