Abstract
The successful management of oncology patients entails the safe use of intravascular catheters. Central venous catheters (CVC), particularly long-term silastic catheters, are commonly used in cancer patients to administer chemotherapy, antibiotics, blood products, and parenteral nutrition. Infection is one of the leading complications of these devices, and catheter-related septicemias represent the most frequent life-threatening complication of intravascular catheters [1–7]. The rate of septicemias associated with noncuffed CVC has ranged from 4 percent to 14 percent [8]. For long-term cuffed silastic catheters, a range of 8–43 percent has been reported [5]. More than 5 million CVCs are inserted in the United States annually [9]. Of those, about 0.5 million are cuffed silastic catheters [10]. Assuming a conservative average septicemia rate of only 8 percent, one would expect at least 400,000 CVC-related septicemias per year.
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Raad, I.I., Fraschini, G. (1995). Intravascular device-related infections in cancer patients. In: Klastersky, J. (eds) Infectious Complications of Cancer. Cancer Treatment and Research, vol 79. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1239-0_10
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DOI: https://doi.org/10.1007/978-1-4613-1239-0_10
Publisher Name: Springer, Boston, MA
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