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Assessment of Myocardial Perfusion with 13N-Ammonia or 82RB

  • Chapter
Cardiac Positron Emission Tomography

Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 165))

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Abstract

Coronary artery disease remains one of the most prevalent diseases in modern industrialized societies. Recent developments in interventional cardiology and vascular surgery require accurate characterization of disease severity and extent for selection of therapy and determination of prognosis. Historically, symptoms of patients have been used to assess the appropriate therapy and to monitor the effect of interventions. With the availability of electrocardiographic criteria, diagnosis of myocardial ischemia has become more objective. However, this method is neither sensitive for detecting regional ischemia nor does it provide the specificity for exclusion of significant coronary artery stenoses. The ability to measure regional myocardial perfusion and function with noninvasive techniques has provided new avenues for assessing the effect of regional coronary artery disease on perfusion and function under rest and stress conditions [1,2]. Radionuclide ventriculography, echocardiography, and 201T1 perfusion imaging have been successfully employed in the diagnostic and prognostic workup of patients with coronary artery disease and have to be considered the standard techniques for this patient population.

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  1. Markus Schwaiger
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  2. Otto Muzik
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  3. Gary D. Hutchins
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Editors and Affiliations

  1. Department of Nuclear Medicine, Technical University in Munich, Klinikum rechts der Isar Ismaninger Strasse 22, D-81675, Munich, Germany

    Markus Schwaiger M.D. (Director and Professor of Medicine, Professor of Internal Medicine) (Director and Professor of Medicine, Professor of Internal Medicine)

  2. Division of Nuclear Medicine Department of Internal Medicine UMH B1 G412 / 0028, University of Michigan Medical Center, 1500 E. Medical Center Drive, Ann Arbor, MI, 48109-0028, USA

    Markus Schwaiger M.D. (Director and Professor of Medicine, Professor of Internal Medicine) (Director and Professor of Medicine, Professor of Internal Medicine)

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Schwaiger, M., Muzik, O., Hutchins, G.D. (1996). Assessment of Myocardial Perfusion with 13N-Ammonia or 82RB. In: Schwaiger, M. (eds) Cardiac Positron Emission Tomography. Developments in Cardiovascular Medicine, vol 165. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1233-8_6

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  • DOI: https://doi.org/10.1007/978-1-4613-1233-8_6

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