Abstract
It has become apparent that successful coronary reperfusion by thrombolysis, angioplasty, or bypass graft surgery is often associated with improvement of function in patients with coronary artery disease. This suggests the presence of dysfunctional but viable myocardium within the area of abnormal wall motion. Myocardial tissue necrosis is a complex pathophysiological process that is dependent upon several factors, such as myocardial metabolism [1,2] and the duration and severity of the blood flow reduction [3–5]. Therefore, in the clinical setting this process can result in asynergic segments containing an admixture of both necrotic and reversibly injured myocardium. Clinically, the identification of such functionally recoverable myocardium in regions of ventricular dysfunction has become an increasingly relevant issue, especially in the management of patients with severely impaired ventricular function.
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Iida, H. et al. (1996). Assessment of Myocardial Viability Using 15O-Water. In: Schwaiger, M. (eds) Cardiac Positron Emission Tomography. Developments in Cardiovascular Medicine, vol 165. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1233-8_13
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DOI: https://doi.org/10.1007/978-1-4613-1233-8_13
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