Abstract
The RAS-mediated signal transduction pathway, which is highly conserved among eukaryotes, plays key roles in multiple cellular and developmental processes including cell proliferation, differentiation and migration. In recent years, a combination of biochemical and genetic studies has allow scientists to identify many key players involved in RAS-mediated signal transduction and has begun to elucidate the mechanisms of activation and regulation of this pathway (see other chapters in this book). From receptor tyrosine kinases (RTKs) to RAS to MAP kinases, the main signal transduction pathway has been well established. The connections between this pathway and several other major signal transduction pathways have also begun to be revealed.
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Han, M., Sundaram, M. (1996). RAS-Mediated Signal Transduction in C. elegans . In: Regulation of the RAS Signaling Network. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1183-6_2
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DOI: https://doi.org/10.1007/978-1-4613-1183-6_2
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