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Breast Cancer

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Current Cancer Therapeutics

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Abstract

Breast cancer is the most frequently diagnosed malignancy in women and the second leading cause of cancer-related deaths in the United States, with approximately 183,000 new cases and 41,000 deaths expected in the year 2000 [1]. The incidence of advanced breast cancer and of death from breast cancer have remained fairly stable, but the number of in situ carcinomas and early-stage breast cancers has increased dramatically; as a result, the proportion of women diagnosed with invasive breast cancer who ultimately die of the disease has strikingly declined. This phenomenon most likely results from early detection through routine mammographic screening and advances in systemic therapy. In fact, retrospective analyses have clearly demonstrated an association between the stage of disease at diagnosis and prognosis with the following 5-year survival data: 97% for noninvasive disease; 78% for invasive disease confined to the breast and/or axilla; and 22% for metastatic disease [1].

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  1. Minetta C. Liu
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  2. Marc E. Lippman
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Liu, M.C., Lippman, M.E. (2001). Breast Cancer. In: Current Cancer Therapeutics. Current Medicine Group, London. https://doi.org/10.1007/978-1-4613-1099-0_6

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