Pulmonary and Cardiovascular Complications of Cancer Therapy

  • Matthew Volm
  • Howard Hochster


Pulmonary complications arising from antineoplastic drugs range from asymptomatic, mild abnormalities (detected by chest radiograph or pulmonary function tests) to fatal pulmonary fibrosis. The incidence and severity of pulmonary toxicity depend on the characteristics of the responsible drug as well as host factors. It is useful to consider three major syndromes that may result from the pharmacologic treatment of cancer: 1) acute drug reactions (usually hypersensitivity), 2) noncardiogenic pulmonary edema, and 3) interstitial pneumonitis/pulmonary fibrosis. Table 28–1 provides a list of the drugs associated with pulmonary complications [1].


Advanced Breast Cancer Cardiac Toxicity Pulmonary Toxicity Vinca Alkaloid Noncardiogenic Pulmonary Edema 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer Science+Business Media New York 2001

Authors and Affiliations

  • Matthew Volm
  • Howard Hochster

There are no affiliations available

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