Immunotoxins pp 281-295 | Cite as

Hormone, lectin and toxin-toxin conjugates

  • Thomas N. Oeltmann
  • Ronald G. Wiley
Part of the Cancer Treatment and Research book series (CTAR, volume 37)


In order to better understand the relative importance of the A and B chains of diphtheria toxin and ricin, chimeras or hybrid toxins have been constructed with diphtheria toxin subunits and ricin subunits coupled to a number of different binding moieties. These experiments have demonstrated wide variations in cytotoxicity depending on the specific combinations of A chain and binding moiety.


Insulin Receptor Cholera Toxin Diphtheria Toxin Hybrid Molecule Placental Lactogen 
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© Kluwer Academic Publishers 1988

Authors and Affiliations

  • Thomas N. Oeltmann
  • Ronald G. Wiley

There are no affiliations available

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