Biopsy Techniques Using the Brown-Roberts Wells (BRW) Stereotactic Guidance System

  • M. Peter Heilbrun
Part of the Topics in neurological surgery book series (TINS, volume 1)


Neurosurgeons have been using stereotactic techniques to localize tumors for more than 20 years. Stereotactic systems such as the Talairach frame refined the technique by combining data from angiography and ventriculography. These systems defined tumor location by relating the position of midline brain structures to the position/displacement of major vessels [12, 20, 24].


Stereotactic Biopsy Probe Track Stereotactic System Stereotactic Technique Probe Trajectory 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. 1.
    Apuzzo MLJ, Chandrasoma PT, Zelman V, et al: Computed tomographic guidance stereotaxis in the management of lesions of the third ventricular region. Neurosurgery 15:502–508, 1984PubMedCrossRefGoogle Scholar
  2. 2.
    Apuzzo MLJ, Sabshin JK: Computed tomo-graphic guidance stereotaxis in the management of intracranial mass lesions. Neurosurgery 12:277–285, 1983PubMedCrossRefGoogle Scholar
  3. 3.
    Brown RA: A computerized tomography-computer graphics approach to stereotaxic localization. J Neurosurg 50:715–720, 1979PubMedCrossRefGoogle Scholar
  4. 4.
    Brown RA, Roberts TS, Osborn AG: Stereotaxic frame and computer software for CT-directed neurosurgical localization. Invest Radiol 15:308–312, 1980PubMedCrossRefGoogle Scholar
  5. 5.
    Heilbrun MP: Computed tomography-guided stereotactic systems. Clin Neurosurg 31:564–581, 1983PubMedGoogle Scholar
  6. 6.
    Heilbrun MP, Brown RA, McDonald PR: Real-time three-dimensional graphics reconstruction using BRW coordinates in a microcomputer environment. Appl Neurophysiol (in press)Google Scholar
  7. 7.
    Heilbrun MP, Roberts TS, Apuzzo ML, et al: Preliminary experience with Brown-RobertsWells (BRW) computerized tomography stereotaxic guidance system. J Neurosurg 59:217–222, 1983PubMedCrossRefGoogle Scholar
  8. 8.
    Heilbrun MP, Roberts TS, Wells TH, et al: Technical Manual: Brown-Roberts-Wells (BRW) CT Stereotaxic Guidance System. Burlington, MA: Radionics, Inc., 1982Google Scholar
  9. 9.
    Heilbrun MP, Sunderland PM, McDonald PR, et al: Brown-Roberts-Wells (BRW) stereotaxic frame modifications to accomplish magnetic resonant image (MRI) guidance in three planes: Axial/coronal/sagittal. Presented at the Annual Meeting of American Association of Neurological Surgeons, Denver Colorado, April, 1986Google Scholar
  10. 10.
    Kelly PJ, Alker GJ: A method for stereotactic laser microsurgery in the treatment of deep-seated CNS neoplasms. Appl Neurophysiol 43:210–215, 1980PubMedGoogle Scholar
  11. 11.
    Kelly PJ, Alker GJ, Goerss S: Computer-assisted stereotactic laser microsurgery for treatment of intracranial neoplasms. Neurosurgery 10:324–331, 1982PubMedCrossRefGoogle Scholar
  12. 12.
    Kelly PJ, Alker GJ Jr, Kall B, et al: Method of computed tomography-based stereotaxic biopsy with arteriographic control. Neurosurgery 14:172–177, 1984PubMedCrossRefGoogle Scholar
  13. 13.
    Kelly PJ, Earnest F, Kall BA, et al: Surgical options for patients with deep-seated brain tumors: Computer-assisted stereotactic biopsy. May. Clin Proc 60:223–229, 1985Google Scholar
  14. 14.
    Leksell L, Jernberg B: Stereotaxis and tomography. A technical note. Acta Neurochir (Wien) 52:1–7, 1980CrossRefGoogle Scholar
  15. 15.
    Maroon JC, Bank WO, Drayer BP, et al: Intracranial biopsy assisted by computerized tomography. J Neurosurg 46:740–744, 1977PubMedCrossRefGoogle Scholar
  16. 16.
    Mundinger F, Birg W, Klar M: Computer-assisted stereotactic brain operations by means including computerized axial tomography. Appl Neurophysiol 41:169–182, 1978PubMedGoogle Scholar
  17. 17.
    Nauta HJW, Guinto FC, Pisharodi M: Arterial bolus contrast medium enhancement for computed tomographically guided stereotactic biopsy. Surg Neurol 22:559–564, 1984PubMedCrossRefGoogle Scholar
  18. 18.
    Ostertag CB, Mennel HD, Kiessling M: Stereotactic biopsy of brain tumors. Surg Neurol 14:275–283, 1980PubMedGoogle Scholar
  19. 19.
    Perry JH, Rosenbaum AE, Lunsford LD, et al: Computed tomography-guided stereotactic surgery: Conception and development of a new stereotactic methodology. Neurosurg 7:376–381, 1980CrossRefGoogle Scholar
  20. 20.
    Scerrati M, Fiorentino A, Fiorentino M, et al: Stereotaxic device for polar approaches in orthogonal systems: Technical note. J Neurosurg 61:1146–1147, 1984PubMedCrossRefGoogle Scholar
  21. 21.
    Sheldon CH, McCann G, Jacques S, et al: Development of a computerized microstereotaxic method for localization and removal of minute CNS lesions under direct 3-D vision. J Neurosurg 52:21–27, 1980CrossRefGoogle Scholar
  22. 22.
    Spiegel EA, Wycis HT, Marks M, et al: Stereotaxic apparatus for operations on the human brain. Science 106:349–350, 1947PubMedCrossRefGoogle Scholar
  23. 23.
    Storrs BB, Walker ML: Use of a CT-guided stereotaxic apparatus in pediatric neurosurgery. Concepts Pediatr Neurosurg 5:214–223, 1985Google Scholar
  24. 24.
    Talairach J, Bancaud J, Szikla G, et al: Approche nouvelle de la neurochirurgie de l’epilepsie. Neurochirurgie 20(Suppl 1):1–98, 1974PubMedGoogle Scholar

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© Martinus Nijhoff Publishing, Boston 1988

Authors and Affiliations

  • M. Peter Heilbrun

There are no affiliations available

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