Abstract
Bone Marrow Transplant (BMT) therapy has been a big success in the treatment of leukemia and other haematopoietic diseases1. Prior to BMT, total body irradiation (TBI) is given to the patient for the purpose of (1) killing leukemia cells in bone marrow, as well as in the whole body, and (2) producing immuno-suppressive status in the patient so that the donor’s marrow cells will be transplanted without rejection. TBI employs a very large field photon beam to irradiate the whole body of the patient. A uniform dose distribution over the entire body is the treatment goal. To prevent the occurrence of a serious side effect (interstitial pneumonia), the lung dose should not exceed a certain level. This novel technique poses various new radiological physics problems. The accurate assessment of dose and dose distribution in the patient is essential. Physical and dosimetric problems associated with TBI are reviewed elsewhere2,3.
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© 1988 Plenum Press, New York
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Ito, A. (1988). Three-Dimensional Dose Calculation for Total Body Irradiation. In: Jenkins, T.M., Nelson, W.R., Rindi, A. (eds) Monte Carlo Transport of Electrons and Photons. Ettore Majorana International Science Series, vol 38. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1059-4_27
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DOI: https://doi.org/10.1007/978-1-4613-1059-4_27
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