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Elastase-α1-Proteinase Inhibitor: An Early Indicator of Septicemia and Bacterial Meningitis in Childhood

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Proteases II

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 240))

Abstract

Neonatal septicemia and meningitis are still a significant cause of morbidity and mortality1,2,3, in addition, systemic bacterial infections as well as bacterial meningitis in childhood are potentially lifethreatening diseases that require prompt recognition and early and appropriate therapy. Recently elastase-α1-proteinase inhibitor complex (E-α1-PI) has been introduced as a valuable indicator of systemic bacterial infections in neonates4.

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References

  1. G. H. McCracken, Jr., Perinatal bacterial diseases, in: “Textbook of Pediatric Infectious Diseases”, R.D. Feigin, ed., W. B. Saunders, Philadelphia (1981).

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  2. G. S. Philip, “Neonatal sepsis and meningitis”, G.K. Hall, Boston (1985).

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  3. Ch. P. Speer, D. Hauptmann, P. Stubbe, and M. Gahr, Neonatal septicemia and meningitis in Göttingen, West-Germany, Pediatr. Infect. Pis. 4:36 (1985).

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  4. Ch. P. Speer, A. Ninjo, and M. Gahr, Elastase-α1-proteinase inhibitor in early diagnosis of neonatal septicemia, J. Pediatr. 108:987 (1986).

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  5. S. Neumann, G. Gunzer, N. Hennrich, and H. Lang, “PMN-Elastase Assay”: Enzyme immunoassay for human polymorphonuclear elastase complexed with α1-proteinase inhibitor, J. Clin. Chem. Clin. Biochem. 22:693 (1984).

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  6. F. K. Tegtmeyer and J. Otte, Early diagnosis of neonatal infections by leukocyte-elastase, Eur. J. Pediatr. 143:249 (1985).

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  7. Ch. P. Speer and M. Gahr, Leukozytenindizes, C-reaktives Protein und PMN-Elastase/α1-Proteinaseinhibitorkomplex in der Frühdiagnostik der neonatalen Sepsis, Monatsschr. Kinderheilkd. 133:595 (1985).

    Google Scholar 

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Author information

Authors and Affiliations

  1. Dept. of Pediatrics, University of Göttingen, Humboldtallee 38, D-3400, Göttingen, Germany

    Ch. P. Speer, M. Rethwilm & M. Gahr

Authors
  1. Ch. P. Speer
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  2. M. Rethwilm
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  3. M. Gahr
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Editor information

Editors and Affiliations

  1. University of Freiburg, Freiburg, Federal Republic of Germany

    Walter H. Hörl

  2. University of Würzburg, Würzburg, Federal Republic of Germany

    August Heidland

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© 1988 Plenum Press, New York

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Speer, C.P., Rethwilm, M., Gahr, M. (1988). Elastase-α1-Proteinase Inhibitor: An Early Indicator of Septicemia and Bacterial Meningitis in Childhood. In: Hörl, W.H., Heidland, A. (eds) Proteases II. Advances in Experimental Medicine and Biology, vol 240. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1057-0_60

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  • DOI: https://doi.org/10.1007/978-1-4613-1057-0_60

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8313-3

  • Online ISBN: 978-1-4613-1057-0

  • eBook Packages: Springer Book Archive

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