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Cathepsin B and D Activity in Human Skeletal Muscle in Disease States

  • Conference paper
Proteases II

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 240))

Abstract

The effects of nutrition and disease state on whole body protein metabolism have been widely studied in recent years, but the distribution of changes among the various body tissues is less known. It is, therefore, important to establish the contribution made by skeletal muscle to whole body protein metabolism in disease state, because skeletal muscle is quantitatively and metabolically the most important body protein “store”1 and remains a good marker of protein-energy malnutrition (PEM) when the protein pools of other tissues and organs become metabolically una vailable 1-3.

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Authors and Affiliations

  1. Istituto di Patologia Medica, University of Trieste, Trieste, Italy

    Gianfranco Guarnieri, Gabriele Toigo, Roberta Situlin, Maria Alessandra Del Bianco & Lucia Crapesi

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  1. Gianfranco Guarnieri
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  2. Gabriele Toigo
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  3. Roberta Situlin
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  4. Maria Alessandra Del Bianco
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  5. Lucia Crapesi
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  1. University of Freiburg, Freiburg, Federal Republic of Germany

    Walter H. Hörl

  2. University of Würzburg, Würzburg, Federal Republic of Germany

    August Heidland

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Guarnieri, G., Toigo, G., Situlin, R., Del Bianco, M.A., Crapesi, L. (1988). Cathepsin B and D Activity in Human Skeletal Muscle in Disease States. In: Hörl, W.H., Heidland, A. (eds) Proteases II. Advances in Experimental Medicine and Biology, vol 240. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1057-0_29

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