Proteases II pp 123-131 | Cite as

Functional Studies of Human Secretory Leukocyte Protease Inhibitor

  • Kjell Ohlsson
  • Magnus Bergenfeldt
  • Peter Björk
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 240)

Abstract

The balance between the concentrations of proteases and their inhibitors is of vital importance to the physiology of a number of tissues including the lung. The proteases in the lung mainly come from infiltrating neutrophils and macrophages and when released from these cells can cause extensive tissue degradation unless they are inactivated by protease inhibitors. One of the major protease inhibitors found in the lung tissue is alpha-l-protease inhibitor (alpha-l-PI) which blocks the activity of neutrophil elastase (1) and cathepsin G (2).

Keywords

Filtration Albumin Urea Pneumonia Titration 

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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Kjell Ohlsson
    • 1
  • Magnus Bergenfeldt
    • 1
  • Peter Björk
    • 1
  1. 1.Department of Surgical PathophysiologyUniversity of Lund, Malmö General HospitalMalmöSweden

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