Skip to main content
SpringerLink
Log in
Book cover

Cerebellum and Neuronal Plasticity pp 225–247Cite as

Climbing Fibre Activity Associated with Unperturbed And Perturbed Step Cycles During Skilled Locomotion In The Cat

  • Conference paper

Part of the book series: NATO ASI Series ((NSSA,volume 148))

Abstract

This chapter reviews the literature relating to the patterns of impulse activity present in cerebellar climbing fibre afferents during locomotion and we give an account of some recent findings of our own regarding activity which occurs in climbing fibres in the lateral part of the anterior lobe vermis in association with unexpected perturbations imposed on the stepping movements of cats undertaking a skilled form of walking.

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Albus, J.S., 1971, A theory of cerebellar function. Mathl. Biosci. 10:25–61.

    Article  Google Scholar 

  • Andersson, G., and Armstrong, D.M., 1987, Complex spikes in Purkinje cells in the lateral vermis (b zone) of the cat cerebellum during locomotion. J. Physiol. 385:107–134.

    PubMed  CAS  Google Scholar 

  • Andersson, G., Ekerot, C-F., Oscarsson, O, and Schouenberg, J., 1986, Convergence of afferent paths to olivo-cerebellar complexes. NATO ARW Workshop Conference on Cerebellum and Neuronal Plasticity. Oxford, England, 7–9 April (This volume)

    Google Scholar 

  • Andersson, G., and Eriksson, L., 1981, Spinal trigeminal and cortical climbing fibre paths to the lateral vermis of the cerebellar anterior lobe in the cat. Exp. Brain Res. 44:71–81.

    Article  PubMed  CAS  Google Scholar 

  • Andersson, G., and Nyquist, J., 1983, Origin and sagittal termination areas of cerebrocerebellar climbing fibre paths in the cat. J. Physiol. 337:257–285.

    PubMed  CAS  Google Scholar 

  • Andersson, G., and Oscarsson, 0, 1978a, Climbing fiber microzones in cerebellar vermis and their projection to different groups of cells in the lateral vestibular nucleus. Exp. Brain Res. 32:565–579.

    PubMed  CAS  Google Scholar 

  • Andersson, G., and Oscarsson, 0, 1978b, Projections to lateral vestibular nucleus from cerebellar climbing fiber zones. Exp. Brain Res. 32:549–564.

    PubMed  CAS  Google Scholar 

  • Andersson, G., and Sjolund B., 1978, The ventral spinoolivocerebellar system in the cat. IV. Spinal transmission after administration of Clonidine and L-Dopa. Exp. Brain Res. 33:227–240.

    CAS  Google Scholar 

  • Armstrong, D.M., 1974, Functional significance of connections of the inferior olive. Physiol. Rev. 54: 358–471.

    PubMed  CAS  Google Scholar 

  • Armstrong, D.M., 1978, The mammalian cerebellum and its contribution to movement control. Internat. Rev. Physiol, Vol. 17, Neurophysiol. 3, pp. 239–294 R. Porter, ed., Univ. Park Press, Baltimore.

    Google Scholar 

  • Armstrong, D.M., 1986, Supraspinal contributions to the initiation and control of locomotion in the cat. Progr. in Neurobiol. 26:273–361.

    Article  CAS  Google Scholar 

  • Armstrong, D.M., Campbell, N.C., Edgley, S.A., Schild, R.F., and Trott, J.R. 1982, Investigation of the olivocerebellar and spinoolivary pathways, pp. 195–232 En: The cerebellum: new vistas, V. Chan-Palay and A.L. Palay, eds., Springer, New York.

    Google Scholar 

  • Armstrong, D.M., and Drew, T., 1984, Discharges of pyramidal tract and other motor cortical neurones during locomotion in the cat. J. Physiol 346:471–495.

    PubMed  CAS  Google Scholar 

  • Armstrong, D.M., and Edgley, S.A., 1984a, Discharges of nucleus inter-positus neurones during locomotion in the cat. J. Physiol. 351:411–432.

    PubMed  CAS  Google Scholar 

  • Armstrong, D.M., and Edgley, S.A., 1984b, Discharges of Purkinje cells in the paravermal part of the cerebellar anterior lobe during locomotion in the cat. J. Physiol. 352, 403–424.

    PubMed  CAS  Google Scholar 

  • Armstrong, D.M., and Rawson, J.A., 1979, Activity patterns of cerebellar cortical neurones and climbing fibre afferents in the awake cat. J. Physiol. 289:425–448.

    PubMed  CAS  Google Scholar 

  • Barmack, N.H., and Hess, D.T., 1980, Multiple-unit activity evoked in dorsal cap of inferior olive of the rabbit by visual stimulation. J. Neurophysiol. 43:151–164.

    PubMed  CAS  Google Scholar 

  • Bloedel, J.R., and Ebner, T.J., 1985, Climbing fiber function: regulation of Purkinje cell responsiveness- pp 247–259 In: Cerebellar functions, J.R. Bloedel, J. Dichgans, and W. Precht, eds., Springer, Berlin.

    Google Scholar 

  • Bloedel, J.R., and Lou, J.-S., 1986, The relation between Purkinje cell simple spike responses and the action of the climbing fiber system in unconditioned and conditioned responses of the forelimb to perturbed locomotion. NATO ARW Workshop Conference on Cerebellum and Neuronal Plasticity, Oxford, England 7–9 April (this volume).

    Google Scholar 

  • Bloedel, J.R., and Roberts, W.J., 1971, Action of climbing fibers in cerebellar cortex of the cat. J. Neurophysiol. 34:17–31.

    PubMed  CAS  Google Scholar 

  • Boylls, C.C., 1980, Contributions to locomotor coordination of an olivocerebellar projection to the vermis in the cat: experimental results and theoretical proposals, pp 321–348 In: The inferior olivary nucleus: Anatomy and Physiology, J. Courville, C de Montigny, and Y. Lamarre, eds., Raven Press, New York.

    Google Scholar 

  • Brodal, A., and Kaw&mura, K., 1980, Olivocerebellar projection: a review. Adv. Anat. Embryol. Cell Biol. 64:1–140.

    Article  Google Scholar 

  • Campbell, N.C., and Hesslow, G., 1986, The secondary spikes of climbing fibre responses recorded from. Purkinje cell axons in cat cerebellum. J. Physiol. 377:225–236.

    PubMed  CAS  Google Scholar 

  • Chan-Palay, V., and Palay, S.L., 1971, Tendril and glomerular collaterals of climbing fibers in the granular layer of the rat’s cerebellar cortex Z. Anat. Entwick. Gesch. 133:247–273.

    Article  CAS  Google Scholar 

  • Demer J.L., and Robinson, D.A., 1982, Effects of reversible lesions and stimulation of olivocerebellar system on vestibuloocular reflex plasticity. J. Neurophysiol. 47:1084–1107.

    PubMed  CAS  Google Scholar 

  • Ebner, T.J., and Bloedel, J.R., 1981, Role of climbing fiber afferent input in determining responsiveness of Purkinje cells to mossy fiber inputs. J. Neurophysiol. 45:962–971.

    PubMed  CAS  Google Scholar 

  • Edgley, S.A., 1983, The discharges of intermediate cerebellar neurons during locomotion in the cat. Ph.D. thesis, University of Bristol.

    Google Scholar 

  • Ghelarducci, B., Ito, M., and Yagi, N., 1975, Impulse discharges from flocculus Purkinje cells of alert rabbits during visual stimulation combined with horizontal head rotation. Brain Res. 87:66–72.

    Article  PubMed  CAS  Google Scholar 

  • Gilbert, P.F.C., and Thach, W.T., 1977, Purkinje cell activity during motor learning. Brain Res. 128:309–328.

    Article  PubMed  CAS  Google Scholar 

  • Grillner, S., 1981, Control of locomotion in bipeds, tetrapods and fish, pp 1179–1236 In: Handbook of Physiology, the nervous system volume 2 Motor Control, part 2, V.B. Brooks, ed., Amer. Physiol. Soc. Bethesda.

    Google Scholar 

  • Gruol, D.L., 1983, Cultured cerebellar neurons: endogenous and exogenous components of Purkinje cell activity and membrane responses to putative transmitters. Brain Res. 263:223–241.

    Article  PubMed  CAS  Google Scholar 

  • Ito, M., 1970, Neurophysiological aspects of the cerebellar motor control system. Int. J. Neurol. 7:162–176.

    PubMed  CAS  Google Scholar 

  • Ito, M., 1972, Neural design of the cerebellar motor control system. Brain Res. 40:81–84.

    Article  PubMed  CAS  Google Scholar 

  • Ito, M., 1984, The cerebellum and neural control. Raven Press, New York.

    Google Scholar 

  • Ito, M., and Simpson, J.I., 1971, Discharges in Purkinje cell axons during climbing fiber activation. Brain Res. 31:215–219.

    Article  PubMed  CAS  Google Scholar 

  • Larsell, O., 1953, The cerebellum of the cat and the monkey. J. Comp. Neurol. 99:135–200.

    Article  PubMed  CAS  Google Scholar 

  • Llinas, R., 1974, Motor aspects of cerebellar control. Physiologist 17:19–46.

    PubMed  CAS  Google Scholar 

  • Llinas, R., 1985, Functional significance of the basic cerebellar circuit in motor coordination, pp. 170–185 In: Cerebellar functions, J.R Bloedel, J. Dichgans and W. Precht, eds., Springer, Berlin.

    Google Scholar 

  • Llinas, R., Baker, R., and Sotelo, C., 1974, Electrotonic coupling between neurons in cat inferior olive. J. Neurophysiol. 37:560–571.

    PubMed  CAS  Google Scholar 

  • Llinas, R., and Volkind, R.A., 1973, The olivo-cerebellar system: Functional properties as revealed by harmaline-induced tremor. Exp. Brain Res. 18:69–87.

    Article  PubMed  CAS  Google Scholar 

  • Llinas, R., and Walton, K., 1977, Significance of the olivo-cerebellar system in compensation of ocular position following unilateral labyrinthectomy. pp. 399–408 In: Control of gaze by brain stem neurons, R. Baker and A. Berthoz, eds., Elsevier, Amsterdam.

    Google Scholar 

  • Llinas, R., and Walton, K., 1979, The role of the olivo-cerebellar system in compensation of ocular position following unilateral labyrinthectomy. pp. 17–36 In: Brain mechanisms in memory and learning, M.A.B. Brazier, ed., Raven Press, New York.

    Google Scholar 

  • Llinas, R., Walton, K., Hillman, D.E., and Sotelo, C., 1975, Inferior olive: its role in motor learning. Science 190:1230–1231.

    Article  PubMed  CAS  Google Scholar 

  • Llinas, R., and Yarom, Y., 1981, Electrophysiology of mammalian inferior olivary neurones in vitro. Different types of voltage-dependent ionic conductances. J. Physiol. 315:549–567.

    CAS  Google Scholar 

  • Mano, N-I., Kanazawa, I., and Yamamoto, K-I., 1986, Complex-spike activity of cerebellar Purkinje cells related to wrist tracking movement in monkey. J. Neurophysiol. 56:137–158.

    PubMed  CAS  Google Scholar 

  • Marr, D., 1969, A theory of cerebellar cortex. J. Physiol. 202:437–470.

    PubMed  CAS  Google Scholar 

  • Martinez, F.F., Crill, W.E., and Kennedy, T.T., 1971, Electrogenesis of cerebellar Purkinje cell responses in cats. J. Neurophysiol. 34:348–356.

    PubMed  CAS  Google Scholar 

  • Miller, S., and Oscarsson, O., 1970, Termination and functional organization of spinoolivo-cerebellar paths, pp. 172–200 In: The cerebellum in health and disease, W.S. Fields and W.D. Willis, eds., W.H. Green Inc. St. Louis.

    Google Scholar 

  • Orlovsky, G.N., and Shik, M.L., 1976, Control of locomotion: a neurophy- siological analysis of the cat locomotor system, pp. 281–317 In: Internal Rev. Physiol, Vol. 10, Neurophysiol. 2, R. Porter, ed., Univ. Park Press, Baltimore.

    Google Scholar 

  • Oscarsson, O., 1973, Functional organization of spinocerebellar paths. pp. 339–380 In: Handbook of sensory physiology Vol 2, Somatosensory system A. Iggo, ed., Springer, Berlin.

    Google Scholar 

  • Oscarsson, O., 1979, Functional units of the cerebellum - sagittal zones and microzones. Trends Neurosci. 2:143–145.

    Article  Google Scholar 

  • Oscarsson, O., 1980, Functional organization of olivary projection to the cerebellar anterior lobe. pp. 279–289 In: The inferior olivary nucleus: anatomy and physiology, J. Courville, C. de Montigny, and Y. Lamarre, eds., Raven Press, New York.

    Google Scholar 

  • Oscarsson, O., and Sjolund, B., 1977a, The ventral spinoolivocerebellar system in the cat. I. Identification of five paths and their termination in the cerebellar anterior lobe. Exp. Brain Res. 28:469–486.

    CAS  Google Scholar 

  • Oscarsson, O., and Sjolund, B., 1977b, The ventral spinoolivocerebellar system in the cat. III. Functional characteristics of the five paths. Exp. Brain Res. 28:505–520.

    CAS  Google Scholar 

  • Phillips, C.G., 1970, Contribution to the discussion on cerebellar function, pp. 243–246 In: Excitatory synaptic mechanisms, P. Andersen, and J.K.S. Jansen, eds., Universitetsforlaget, Oslo.

    Google Scholar 

  • Schulman, J.A., and Bloom, F.E., 1981, Golgi cells of the cerebellum are inhibited by inferior olive activity. Brain Res. 210:350–355.

    Article  PubMed  CAS  Google Scholar 

  • Shik, M.L. and Orlovsky, G.N., 1976, Neurophysiology of locomotor automatism. Physiol. Rev. 56:465–501.

    PubMed  CAS  Google Scholar 

  • Simpson, J.I., and Alley, K.E., 1974, Visual climbing fiber input to rabbit estibulocerebellum: a source of direction-specific information. Brain Res. 82:302–308.

    Article  PubMed  CAS  Google Scholar 

  • Strata, P., 1985, Inferior olive: functional aspects, pp. 230–246 In: Cerebellar functions, J.R. Bloedel, J. Dichgans, and W. Precht, eds. Springer, Berlin.

    Google Scholar 

  • Thach, W.T., 1967, Somatosensory receptive fields of single units in cat cerebellar cortex. J. Neurophysiol. 30:675–696.

    PubMed  Google Scholar 

  • Trott, J.R., and Armstrong, D.M., 1986, Olivo-cortico-nuclear organization within lobule V of the anterior lobe of the cat cerebellum• In: New concepts in cerebellar neurobiology, J.S. King, ed., Liss, New York (in press).

    Google Scholar 

  • Udo, M., Matsukawa, K., Kamei, H., Minoda, K., and Oda, Y., 1981, Simple and complex spike activities of Purkinje cells during locomotion in the cerebellar vermal zones of decerebrate cats. Exp. Brain Res. 41:292–300.

    Article  PubMed  CAS  Google Scholar 

  • Voogd, J., and Bigare, F., 1980, Topographical distribution of olivary and corticonuclear fibers in the cerebellum: a review, pp. 207–234 In: The inferior olivary nucleus: anatomy and physiology, J. Courville, C. de Montigny, and Y. Lamarre, eds., Raven Press, New York.

    Google Scholar 

  • Wilson, W.C., and Magoun, H.W., 1945, The functional significance of the inferior olive in the cat. J. Comp. Neurol. 83:69–77.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Physiology, The Medical School, University of Bristol, Bristol, England

    D. M. Armstrong

  2. Institute of Physiology and Biophysics, Lund University, Lund, Sweden

    G. Andersson

Authors
  1. D. M. Armstrong
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. G. Andersson
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Neuroscience and Behaviour Group, Department of Anatomy, University College London, 3 Malet Place, London, WC1E 7JG, England, UK

    Mitchell Glickstein  & Christopher Yeo  & 

  2. Magdalen College, Oxford University, Oxford, England

    John Stein

Rights and permissions

Reprints and permissions

Copyright information

© 1987 Plenum Press, New York

About this paper

Cite this paper

Armstrong, D.M., Andersson, G. (1987). Climbing Fibre Activity Associated with Unperturbed And Perturbed Step Cycles During Skilled Locomotion In The Cat. In: Glickstein, M., Yeo, C., Stein, J. (eds) Cerebellum and Neuronal Plasticity. NATO ASI Series, vol 148. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0965-9_15

Download citation

  • DOI: https://doi.org/10.1007/978-1-4613-0965-9_15

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8268-6

  • Online ISBN: 978-1-4613-0965-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation