Abstract
Hair and nails have obvious advantages as well as disadvantages as tissues for biological monitoring, which have been discussed repeatedly by many authors from different viewpoints such as environmental and occupational health, nutritional sciences and forensic medicine (Hambidge, 1982; Jenkins, 1979; Katz, 1979; Klevay, 1978; Laker, 1982; Maugh, 1978; Pankhurst and Pate, 1979; Rivlin, 1983; Schroeder and Nason, 1969; Toribara and Muhs, 1984). Problems of analysis using hair and nails will be reviewed in this chapter. However, it must be mentioned that the use of hair and nails has not been studied fully for correlation with environmental and occupational exposure and for representing the critical organ concentration. If we follow the critical organ concept, as accepted by the Subcommittee of Toxicology of Metals (Nordberg, 1976), it would be necessary to determine the concentration of specific metals in critical organs and to relate that concentration to the level in hair and nails. In this sense, our knowledge of many toxic metals is still very limited.
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Suzuki, T. (1988). Hair and Nails: Advantages and Pitfalls when used in Biological Monitoring. In: Clarkson, T.W., Friberg, L., Nordberg, G.F., Sager, P.R. (eds) Biological Monitoring of Toxic Metals. Rochester Series on Environmental Toxicity. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0961-1_30
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