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Biological Monitoring of Toxic Metals pp 567–602Cite as

Biological Monitoring of the Human Placenta

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Part of the book series: Rochester Series on Environmental Toxicity ((RSET))

Abstract

The placenta supports the development and growth of the fetus in utero. Structural or functional placental abnormalities produced by metals may compromise fetal development and alter function of the individual after birth and even throughout life. It is therefore important to improve diagnostic methods available to define the location, anatomy and function of the placenta as well as the presence and distribution of metals in the placenta. These assessments include maternal blood flow in the intervillous space, fetal blood flow in the villi, overlap of maternal and fetal blood flow, placental uptake and transport of substrates to the fetal circulation, and placental metabolic state. Nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) are additional noninvasive techniques which may prove even more useful in attaining some of these goals.

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Authors and Affiliations

  1. Department of Obstetrics/Gynecology, University of Rochester, School of Medicine and Dentistry, Rochester, New York, 14642, USA

    Richard K. Miller

  2. Department of Pharmacology, University of Rochester, School of Medicine and Dentistry, Rochester, New York, 14642, USA

    Richard K. Miller

  3. Department of Biophysics, University of Rochester, School of Medicine and Dentistry, Rochester, New York, 14642, USA

    Richard K. Miller

  4. Division of Toxicology, University of Rochester, School of Medicine and Dentistry, Rochester, New York, 14642, USA

    Richard K. Miller

  5. Department of Obstetrics/Gynecology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, 77205, USA

    Donald R. Mattison & David Plowchalk

  6. Department of Pharmacology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, 77205, USA

    Donald R. Mattison & David Plowchalk

  7. Division of Reproductive Pharmacology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, 77205, USA

    Donald R. Mattison & David Plowchalk

  8. Division of Toxicology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, 77205, USA

    Donald R. Mattison & David Plowchalk

  9. Division of Interdisciplinary Toxicology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, 77205, USA

    Donald R. Mattison & David Plowchalk

  10. Division of Reproductive and Developmental Toxicology, The National Center for Toxicological Research, Jefferson, Arkansas, 72079, USA

    Donald R. Mattison & David Plowchalk

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  1. Richard K. Miller
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Editor information

Editors and Affiliations

  1. University of Rochester Shool of Medicine, Rochester, New York, USA

    Thomas W. Clarkson

  2. The Karolinska Institute, Stockholm, Sweden

    Lars Friberg

  3. University of Umea, Umea, Sweden

    Gunnar F. Nordberg

  4. Stauffer Chemical Company, Farmington, Connecticut, USA

    Polly R. Sager

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© 1988 Plenum Press, New York

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Miller, R.K., Mattison, D.R., Plowchalk, D. (1988). Biological Monitoring of the Human Placenta. In: Clarkson, T.W., Friberg, L., Nordberg, G.F., Sager, P.R. (eds) Biological Monitoring of Toxic Metals. Rochester Series on Environmental Toxicity. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0961-1_28

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  • DOI: https://doi.org/10.1007/978-1-4613-0961-1_28

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