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Biological Monitoring of Toxic Metals pp 75–83Cite as

Biological Monitoring

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Part of the book series: Rochester Series on Environmental Toxicity ((RSET))

Abstract

Biological monitoring may be defined as a systematic or repetitive measurement and assessment of agents or their metabolites either in tissues or secretions, to evaluate the uptake of a chemical and the health risk involved, with the purpose of prevention of health effects by corrective actions as needed (modified from Berlin et al., 1984).

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References

  • ACGIH, 1984, American Conference of Government Industrial Hygienists (ACGIH): TLYs threshold limit values for chemical substances and physical agents in the work environment and biological exposure indices with intended changes for 1984-1985. Supplemental Documentation 1984, ACGIH, Cincinnati, Ohio.

    Google Scholar 

  • Adams, D.B., Brown, S.S., Sunderman, F.W., Jr., and Zachariassen, H., 1978, Interlaboratory comparisons of nickel analyses in urine by atomic absorption spectrometry, Clin. Chem., 24: 862–867.

    PubMed  CAS  Google Scholar 

  • Aitio, A., 1980, Quality control in the occupational toxicology laboratory, WHO, Regional Office for Europe, Health aspects of chemical safety, Interin Document 4, Copenhagen.

    Google Scholar 

  • Aitio, A., and Jarvisalo, J., 1984, Biological monitoring of occupational exposure to toxic chemicals. Collection, processing and storage of specimens, Pure Appl. Chem., 56:549–566; Also published in Ann. Clin. Lab. Sci., 15: 121–139, 1985.

    Google Scholar 

  • Aitio, A., and Jarvisalo, J., 1986, Levels of welding fume components in tissues and body fluids, in: “Health Hazards and Biological Effects of Welding Fumes and Gases,” R.M. Stern, A. Berlin, A.C. Fletcher and J. Jarvisalo, eds, pp. 169–179, Excerpta Med. Congr. Ser. 676, Elsevier, Amsterdam.

    Google Scholar 

  • Aitio, A., Jarvisalo, J., and Stoeppler, M., 1986a, Sampling and sample storage, in: “Trace Metal Analysis in Biological Specimens,” M. Stoeppler, ed., Biomed. Publ., Foster City, CA, in press.

    Google Scholar 

  • Aitio, A., Jarvisalo, J., Riihimaki, V. and Hernberg, S., 1986b, Biological monitoring, in: “Occupational Medicine,” 2nd Edition, C. Zenz, ed., in press.

    Google Scholar 

  • Aitio, A., Riihimaki, V., and Vainio, H., eds., 1984, Biological monitoring and surveillance of workers exposed to chemicals, Hemisphere, Washington, DC.

    Google Scholar 

  • Alessio, L., Berlin, A., Roi, R., and Boni, M., eds., 1983, Industrial health and safety. Human biological monitoring of industrial chemicals series, CEC, Luxembourg.

    Google Scholar 

  • Alstrom, T., Grasbeck, R., Hjelm, M., and Skandsen, S., 1975, Recommendations concerning the collection of reference values in clinical chemistry, Scand. J. Clin. Lab. Invest., 35, Suppl. 144: 1.

    CAS  Google Scholar 

  • Baselt, R.C., 1980, “Biological Monitoring Methods for Industrial Chemicals”, Biomed. Publ., Davis, CA.

    Google Scholar 

  • Berlin, A., Yodaiken, R.E. and Henman, B.A., eds., 1984, “Assessment of Toxic Agents at the Work Place”. Roles of Ambient and Biological Monitoring, Nijhoff Publ., The Hague.

    Google Scholar 

  • Boone, J., Hearn, T. and Lewis, S., 1979, Comparison of interlaboratory results for blood lead with results from a definitive method, Clin. Chem., 25: 389–393.

    PubMed  CAS  Google Scholar 

  • Cronin, E., Di Michael, A.O. and Brown, S.S., 1980, Oral challenge in nickel-sensitive women with hand excema. In: “Nickel Toxicology,” S.S. Brown, F.W. Sunderman, Jr. eds., pp. 149–152, Academic Press.

    Google Scholar 

  • Deutsche Forschungsgemeinschaft (DFG), 1983, “Maximale Arbeitsplatz-konzentrationen und Biologische Arbeitsstofftoleranzwerte,” Verlag Chemie, Weinheim, BRD.

    Google Scholar 

  • Gipson, R.S., 1980, Hair as a biopsy material for the assessment of trace element status in infancy, J. Human Nutr., 34: 405–416.

    Google Scholar 

  • Gompertz, D., 1985, “Laboratory Methods for Biological Monitoring,” 2nd Edition, Health and Safety Executive, London.

    Google Scholar 

  • Hartung, M., Schaller, K.-H., Kentner, M., Weltle, D., and Valentin, H., 1983, Untersuchungen zur Cobalt-Belastung in verschiedenen Gewerbezweigen, Arbeitsmed. Sozi al med. Praventivmed. 18: 73–75.

    Google Scholar 

  • Hilderbrand, D.C., and White, D.H., 1974, Trace-element analysis in hair: An evaluation, Clin. Chem., 20: 148–151.

    PubMed  CAS  Google Scholar 

  • Kalliomaki, P.-L., Kalliomaki, K., and Moilanen, M., 1986, A mobile magnetopneumograph with dust quality sensing, in: “Health Hazards and Biological Effects of Welding Fumes and Gases” R.M. Stern, A. Berlin, A.C. Fletcher, J. Jarvisalo, eds., pp. 215–218, Excerpta Medica Int. Congr. Ser. 676, Elsevier, Amsterdam.

    Google Scholar 

  • Lauwerys, R., 1983a, “Industrial Chemical Exposure: Guidelines for biological Monitoring,” Biomed. Publ., Davis, CA.

    Google Scholar 

  • Lauwerys, R., 1983b, In vivo tests to monitor body burdens of toxic metals in man, in: “Chemical Toxicology and Clinical Chemistry of Metals,” S.S. Brown and J. Savory, eds., Academic Press, London.

    Google Scholar 

  • Lauwerys, R., Buchet, J.-P., Roels, A., Berlin, A., and Smeets, J., 1975, Intercomparison program of lead, mercury and cadmium analysis in blood, urine and aqueous solutions, Clin. Chem., 21: 551–557.

    PubMed  CAS  Google Scholar 

  • Lippmann, N., 1986, Magnetopneumography as a tool for measuring lung burden of industrial aerosols, in: “Health Hazards and Biological Effects of Welding Fumes and Gases,”R.M. Stern, A. Berlin, A.C. Fletcher and J. Jarvisalo, eds, pp. 199–213, Excerpta Med. Congr. Ser. 676, Elsevier, Amsterdam.

    Google Scholar 

  • Needleman, H., Gunnoe, C., Leviton, A., Reed, R., Peresie, H., Maber, C., and Barrett, P., 1979, Deficits in psychologic and classroom performance of children with elevated dentine lead levels, New Engl. J. Med., 300: 689–695.

    Article  PubMed  CAS  Google Scholar 

  • Piotrowski, J.K., Trojanowska, B. and Mogilnicka, E.M., 1975, Excretion kinetics and variability in urinary mercury in workers exposed to mercury vapor, Internat. Archiv. Occupât. Environ. Health, 35: 245–256.

    Article  CAS  Google Scholar 

  • Robertson, D.E., 1968, Role of contamination in trace element analysis of sea water, Anal. Chem., 40: 1067.

    Article  CAS  Google Scholar 

  • Roi, R., Town, W.G., Hunter, W.G., and Alessio, L., 1983, Occupational Health Guidelines for Chemical Risks, CEC, Luxembourg.

    Google Scholar 

  • Scott, M.C. and Chettle, D.R., 1986, In vivo elemental analysis in occupational medicine, Scand. J.: Work Environ. Hlth., 12: 81–96.

    CAS  Google Scholar 

  • Stoeppler, M., 1980, Analysis of nickel in biological materials and natural waters, in: “Nickel in the Environment,” J.O. Nriagu, ed., pp. 661–821, John Wiley and Sons, New York.

    Google Scholar 

  • Sunderman, F.W., Jr., Aitio, A., Morgan, L.G. and Norseth, T., 1986,

    Google Scholar 

  • Biological monitoring of nickel exposures, Toxicol. Ind. Hlth., 2:17–78.

    Google Scholar 

  • Sunderman, F.W., Jr., Brown, S.S., Stoeppler, M. and Tonks, D.B., 1982, Interlaboratory evaluations of nickel and cadmium analyses in body fluids, in: “IUPAC Collaborative Studies in Chemical Analysis,” H. Egan and T.S. West, eds., pp. 25–35, Pergamon Press, Oxford and New York.

    Google Scholar 

  • Sunderman, F.W., Jr., Crisostomo, C., Reid, M.C., Hopfer, S.M., and Nomoto, S., 1984, Rapid analysis of nickel in serum and blood by electrothermal atomic absorption spectrophotometry, Ann. Clin. Lab. Sci., 232–241.

    Google Scholar 

  • Vahter, M., 1982, “Assessment of Human Exposure to Lead and Cadmium through Biological Monitoring,” Natl. Swedish Inst. Environ. Med., Dept. Environ. Hyg., Karolinska Institute, Stockholm. Vainio, H., Hemminki, K. and Wilbourn, J., 1985, Data on the carcinogenicity of chemicals in the IARC Monographs programme, Carcinogenesis, 6: 1653–1665.

    Google Scholar 

  • Versieck, J.M.J., and Speecke, A.B.H., 1972, Contaminations induced by collection of liver biopsies and human blood, in: “Nuclear Activation Techniques in the Life Sciences,” IAEA, pp. 39–49, Vienna.

    Google Scholar 

  • WHO, 1980, “Recommended Health-Based Limits in Occupational Exposure to Heavy Metals,” Tech. Rep. Ser. 647, WHO, Geneva.

    Google Scholar 

  • WHO, 1981, “External Quality Assessment of Health Laboratories,” Euro. Rep. Stud. 36, WHO Euro., Copenhagen.

    Google Scholar 

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Author information

Authors and Affiliations

  1. Institute of Occupational Health, Topeliuksenkatu 41a A, SF-00250, Helsinki, Finland

    Antero Aitio

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  1. Antero Aitio
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Editor information

Editors and Affiliations

  1. University of Rochester Shool of Medicine, Rochester, New York, USA

    Thomas W. Clarkson

  2. The Karolinska Institute, Stockholm, Sweden

    Lars Friberg

  3. University of Umea, Umea, Sweden

    Gunnar F. Nordberg

  4. Stauffer Chemical Company, Farmington, Connecticut, USA

    Polly R. Sager

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© 1988 Plenum Press, New York

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Aitio, A. (1988). Biological Monitoring. In: Clarkson, T.W., Friberg, L., Nordberg, G.F., Sager, P.R. (eds) Biological Monitoring of Toxic Metals. Rochester Series on Environmental Toxicity. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0961-1_2

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  • DOI: https://doi.org/10.1007/978-1-4613-0961-1_2

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-306-42809-8

  • Online ISBN: 978-1-4613-0961-1

  • eBook Packages: Springer Book Archive

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