Mechanism of the Inhibition of Liver HepatoCarcinogenesis Promotion by S-Adenosyl-L-Methionine

  • Francesco Feo
  • Renato Garcea
  • Lucia Daino
  • Rosa Pascale
Conference paper


The identification and subsequent characterization of preneoplastic lesions in different tissues, in animals subjected to chemical carcinogens and in man, gives rise to a new and attractive outlook in the prevention of cancer development. It might be possible, by modulating the promotion and progression steps of carcinogenesis to inhibit the development of preneoplastic tissue as well as its progression to neoplasia. The disappearance of preneoplastic lesions has been recently obtained after treatment with certain antioxidants, hypolipidemic drugs, dehydroepiandrosterone and some other related hormones1–5.


Labelling Index Partial Hepatectomy Hyperplastic Nodule Liver Carcinogenesis Triphasic Model 
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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Francesco Feo
    • 1
  • Renato Garcea
    • 1
  • Lucia Daino
    • 1
  • Rosa Pascale
    • 1
  1. 1.Istituto di Patologia generale dell’Università di SassariSassariItaly

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