Endocrine Exophthalmos - Natural History and Results of Treatment

  • Ekkehard Schifferdecker
  • Karl Schöffling

Abstract

The appearance of endocrine ophthalmopathy (B.O.) is pathognomonic For Graves’ disease, but its outbreak is unpredictable, not correlated with the course and treatment of thyrotoxicosis, and often causing major therapeutic problems. Therefore, history of e.o. and therapeutic efforts in 191 patients suffering from Graves’ disease and seen in our outpatient ward were analysed retrospectively.

Keywords

Cyclosporin Cyclophosphamide Tempo Thyrotoxicosis Exophthalmos 

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Literature

  1. 1.
    Bartels, E.C., M. Irie: in:”Advances in thyroid research”, R. Pitt-Rivsrs, ed., PBrgamon Press, New York 1961Google Scholar
  2. 2.
    Brain, R.: Cortisone in exophthalmos, Lancet 1:6 (1955)Google Scholar
  3. 3.
    Day, R.M: Hyperthyroidism: clinical manifestations of eye changes, in..- “The thyroid: a fundamental and clinical text”, S.C. Werner, S.H. Ingbar, ed., Harper and Row, New York 1978Google Scholar
  4. 4.
    Garber, M.I.: Msthylprsdnisolons in ths trsatmsnt of Exophthalmos, Lancet 1:958 (1966)PubMedCrossRefGoogle Scholar
  5. 5.
    Gorman, C.A.: The presentation and management of endocrine ophthalmopathy, Clin. Endocr. Metab. 7:67 (1978)CrossRefGoogle Scholar
  6. 6.
    Gorman, C.A.: Temporal rslationship Between onset of Graves’ ophthalmopathy and diagnosis of thyrotoxicosis, Mayo Clin. Proc. 58:515 (1983)PubMedGoogle Scholar
  7. 7.
    Koch, H.-H.: Ergebnisse in der Therapie der endokrinen Oph - thalmopathie in den Jahren 1978-1981, in: “Schilddrüse 1981”, P.C. Scriba, K.-H. Rudorff, B. Weinheimer, eds., Thieme Stuttgart - New York 1982Google Scholar
  8. 8.
    Schatz,H., S.F.Grabe, U. Schröder, C. Eissnhardt, H. Müller, G.-L. Fangswisch: Therapiesrgsbnisse bei 161 Patienten mit endokriner Orbitopathie, in: “Bchilddruse 1981”, P.C. Scriba, K. -H. Rudorff, B. Weinheimer, eds., Thieme Stuttgart - New York 1982Google Scholar
  9. 9.
    Uhlenbrock, D., H.J. Fischsr, R. Rohwerder: Strahlentherapie der endokrinen Ophthalmopathis - Auswertung von 56 Fällen, Strahlentherapie 160:485 (1984)PubMedGoogle Scholar
  10. 10.
    Utech, C., K.G. Wulle, E.U. Bieler, P. Pf annenetiel, N. Panitz, H. Kisfer: Treatment of severe Graves’ ophthalmopathy with cyclosporin A. Acta endocr. 110:493 (1985)PubMedGoogle Scholar
  11. 11.
    . Werner, S.C.: Prednisons in Bmsrgsncy trsatmsnt of malignant Exophthalmos, Lancet 1:1004 (1966)CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1997

Authors and Affiliations

  • Ekkehard Schifferdecker
    • 1
  • Karl Schöffling
    • 1
  1. 1.Department of Endocrinology, Center of Internal MedicineUniversity HospitalFrankfurt am MainGermany

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