Antiidiotypic Blocking of Graves′ Disease Biologic Activity with Autologous Sera But Not Consistently with Homologous Sera: Evidence for Polyclonality of Thyroid Receptor Antibodies (Trab)

  • R. Paschke
  • J. Teuber
  • U. Schwedes
  • K. H. Usadel

Abstract

Although there is multiple evidence for the functional heterogeneity and polyclonality of TRAb (1 - 3) both statements are questioned by some investigators (4, 5). Furthermore there is growing evidence for an idiotypic-antiidiotypic regulation of Graves disease and other autoimmune diseases (6, 7).

Keywords

Thymidine Goiter 

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References

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Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • R. Paschke
    • 1
  • J. Teuber
    • 1
  • U. Schwedes
    • 1
  • K. H. Usadel
    • 1
  1. 1.II. Medical Dept.Klinikum Mannheim der Universitat HeidelbergMannheim 1Germany

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