Some Aspects of Cell Mediated Autoimmunity in Endemic Nodular Goitre

  • A. Balsamo
  • F. Botto Micca
  • P. A. Merlin
  • V. De Filippis
  • A. Stramignoni

Abstract

The diagnosis of autoimmune thyroid disease (ATD), when suspected as a result of clinical, hormonal, instrumental (U.S., scintigraphy), and immunological findings, may be confirmed by conventional hystology or immunochemical stainings also applicable to tissue or simple cells obtained by fine needle biopsy. This has been reported by several authors who investigated lymphoid cell subsets from thyroids of patients with suspected ATD1,2,3,4. In this present work, and in previous works, we looked for the presence and possibly the meaning of lymphoid tissue infiltrating the thyroid (LI) of goitrous patients living in an iodine deficient area. In these patients frequently we found high prevalence of antithyroid autoantibodies at low title and histological findings of focal thyroiditis.

Keywords

Iodine Adenoma Germinal Paraffin Thyroiditis 

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Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • A. Balsamo
    • 1
  • F. Botto Micca
    • 2
  • P. A. Merlin
    • 1
  • V. De Filippis
    • 1
  • A. Stramignoni
    • 2
  1. 1.Division and Laboratory of Endocrinology of Mauriziano HospitalTurinItaly
  2. 2.Department of Pathology of the University of TurinTurinItaly

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