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Cell Biology of Mouse Mammary Carcinogenesis in Organ Culture

  • Chapter
Cellular and Molecular Biology of Mammary Cancer

Abstract

Mammary carcinogenesis including human breast cancer is a major cause of premature death of women in different parts of the world. Breast cancer also is the second highest cause of mortality of women in the United States. Thus understanding of the pathgenesis of the mammary cancer has been of principal concern of the experimental oncologists

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References

  1. Bittner, J. J. Cancer in mice. In: Research Conference on Cancer, (F. R. Moulton, ed) Amer. Assoc. Adv. Sci. pp. 63–96, 1945.

    Google Scholar 

  2. Barnum, C. P. and Huseby, R. A. Chemical and physical characteristics of preparations containing the milk agent virus. A review. Cancer Res. 10: 523 – 529, 1950.

    PubMed  CAS  Google Scholar 

  3. Bittner, J. J. Mammary cancer in C3H mice of different sublines and their hybrids. J. Nat. Cancer Inst. 16: 1263 – 1956, 1956.

    PubMed  CAS  Google Scholar 

  4. Bern, H. A. and Nandi, S. Recent studies of the hormonal influence in mouse mammary tumorigenesis. Prog. Exp. Tumor Res. 2: 91 – 145, 1961.

    Google Scholar 

  5. Nandi, S. Interactions among hormonal, viral and genetic factors in mouse mammary tumorigenesis. Can Cancer Conf. 6: 69 – 81, 1966.

    Google Scholar 

  6. Bishop, M. J. Retro viruses. Ann. Rev. Biochem. 47: 35 – 88, 1978.

    Article  PubMed  CAS  Google Scholar 

  7. Baltimore, D. RNA tumor viruses. Cold Spring Harbor Symp. Quant. Biol. 39: 1187 – 1200, 1974.

    Google Scholar 

  8. Sarker, N. H., Moor, D. H. and Nowinski, R. C. In:RNA Viruses and Host Genome in Oncogenesis, 1972.

    Google Scholar 

  9. Klein, G. In:Viral Oncology, Raven Press, NY, 1980.

    Google Scholar 

  10. Davidson, E. H. In:Gene Activity in Early Development, Academic Press, NY, 1976.

    Google Scholar 

  11. Barenblum, I. and Shubik, P. A new quantitative approach to study of the stages of chemical carcinogenesis in mouse skin. Brit. J. Cancer 1: 379 – 391, 1947.

    Article  Google Scholar 

  12. Huggins, C., Grand, L. C. and Brilliantes, F. P. Mammary cancer induced by a single feeding of polynuclear hydrocarbons and its suppression. Nature 189: 204 – 207, 1961.

    Article  PubMed  CAS  Google Scholar 

  13. Medina, D. Mammary tumorigenesis in chemical carcinogen treated mice. I. Incidence in BALB/c and C57BL mice. J. Nat. Cancer Inst. 53: 213 – 221, 1974.

    PubMed  CAS  Google Scholar 

  14. Ichinose, R. R. and Nandi, S. Influence of hormones on lobuloalveolar differentiation of mouse mammary gland in vitro. J. Endocrinol. 35: 331 – 340, 1966.

    Article  PubMed  CAS  Google Scholar 

  15. Banerjee, M. R., Wood, B. G. and Washburn, L. L. Brief communication: Chemical carcinogen-induced alveolar nodules in organ culture of mouse mammary gland. J. Nat. Cancer Inst. 53: 1387 – 1393, 1974.

    PubMed  CAS  Google Scholar 

  16. Lin, F. K., Banerjee, M. R. and Crump, L. R. Cell cycle-related hormone carcinogen interaction during chemical carcinogen induction of nodule-like mammary lesions in organ culture. Cancer Res. 36: 1607 – 1614, 1976.

    PubMed  CAS  Google Scholar 

  17. DeOme, K. B. The mammary tumor system in mice. A brief review. In:Viruses Inducing Cancer (J. Burdette, ed) Univ. of Utah Press, Salt Lake City, pp. 127–137, 1966.

    Google Scholar 

  18. Medina, D. Preneoplastic lesions in murine mammary cancer. In: Methods in Cancer Research (H. Busch, ed) Academic Press, NY, Vol. 7, pp. 3–53, 1973.

    Google Scholar 

  19. Nandi, S. and McGrath, C. S. Mammary neoplasia in mice. Adv. Cancer Res. 17: 353 – 414, 1973.

    Article  Google Scholar 

  20. Banerjee, M. R. Responses of mammary cells to hormones. Intern’1 Rev. Cytology 4: 1 – 97, 1976.

    Article  CAS  Google Scholar 

  21. Ganguly, R., Mehta, N. M., Ganguly, N. and Banerjee, M. R. Glucocorticoid modulation of casein gene transcription in mouse mammary gland. Proc. Natl. Acad. Sci. U.S.A. 76: 6466 – 6470, 1979.

    Article  PubMed  CAS  Google Scholar 

  22. Bodell, W. J. and Banerjee, M. R. DNA repair in normal and preneoplastic mammary tissue. Cancer Res. 38: 736–740

    Google Scholar 

  23. Banerjee, M. R., Terry, P. M., Sakai, S. and Lin, F. K. Regulation of mRNA and specific milk protein in mammary gland. In:Hormone Research III (N. Norvell and T. Shellenberger, eds) Hemisphere, Publishing Corp., Washington, DC, pp. 281–306, 1977.

    Google Scholar 

  24. Medina, D. and DeOme, K. B. Influence of mammary tumor virus on the tumor-producing capabilities of nodule outgrowth free of mammary tumor virus. J. Nat. Cancer Inst. 40: 1303 – 1308, 1968.

    PubMed  CAS  Google Scholar 

  25. Medina, D. Preneoplasia in breast cancer. In:Breast Cancer (W. L. McGuire, ed) Plenum Publishing, NY. Vol. 2, pp 47–102, 1978.

    Google Scholar 

  26. DeOme, K. B., Miyamoto, M. J., Osborn, R. C., Guzman, R. C. and Lum, K. Detection of inapparent nodule-transformed cells in the mammary gland tissues of virgin female BALB/cfC3H mice. Cancer Res. 38: 2103 – 2111, 1978.

    PubMed  CAS  Google Scholar 

  27. Farber, E. and Cameron, R. Sequential analysis of cancer development. Adv. Cancer Res. 31, 125 – 226, 1980.

    Article  PubMed  CAS  Google Scholar 

  28. Banerjee, M. R. and Antoniou, M. Steroid and polypeptide hormone interaction in milk-protein gene expression. In:Biochemical Actions of Hormones (G. Litwack, ed) Academic Press, NY, Vol. 12, pp 237–287, 1985.

    Google Scholar 

  29. Wellings, S. R., Jensen, H. M. and Marcum, R. G. An atlas of subgross pathology of the human breast with special reference to precancerous lesions. J. Nat. Cancer Inst. 55: 231 – 274, 1975.

    PubMed  CAS  Google Scholar 

  30. Adamson, R. D. Banerjee, M. R. and Medina, D. Susceptibility of mammary tumor virus-free BALB/c mice in DNA synthesis to 3-methyl-cholanthrene tumorigenesis. J. Nat. Cancer Inst. 46: 899 – 907, 1971.

    PubMed  CAS  Google Scholar 

  31. Banerjee, M. R., Wood, B. G., Lin, F. K. and Crump, L. R. Organ culture of the whole mammary gland of the mouse. In:Tissue Culture Assoc. Manual (K. K. Sanford, ed) Tissue Culture Assoc., Rockville, MD. vol 2, pp 457–462, 1976.

    Google Scholar 

  32. Banerjee, M. R. and Antoniou, M. Serum-free culture of the isolated whole mammary organ of the mouse: A model for the study of differentiation and carcinogenesis. In:Cell Culture Methods for Molecular and Cell Biology (D. W. Barnes, D. A. Sirbasku and G. H. Sato, eds) Alan R. Liss, Inc., NY, Vol. 2, pp 143–169, 1984.

    Google Scholar 

  33. Berjee, M. R. An in vitromodel for neoplastic transfortation of epithelial cells in an isolated whole mammary organ of the mouse. In:In VitroModel for Cancer Research (M. Weber and L. Sekely, eds) CRC Press, Boca Raton, FL, in press, 1985

    Google Scholar 

  34. Elias, J. J. Cultivation of adult mouse mammary gland in hormone enriched synthetic medium. Science 126, 842 – 844, 1957.

    Article  PubMed  CAS  Google Scholar 

  35. Mehta, R. G. and Banerjee, M. R. Progesterone receptor(s) and possible role of prolactin for its regulation in the mammary gland. J. Cell Biol. 63: 220a, 1974.

    Google Scholar 

  36. Ganguly, N., Ganguly, R., Mehta, N. M., Crump, L. R. and Banerjee, M. R. Simultaneous occurrence of pregnancy-like lobuloalveolar morphogenesis and casein gene expression in a culture of the whole mammary gland. In Vitro17: 55 – 670, 1981.

    Article  PubMed  CAS  Google Scholar 

  37. Tonelli, Q. J. and Sorof, S. Epidermal growth factor requirement for development of cultured mammary glands. Nature 285, 250 – 252, 1980.

    Article  PubMed  CAS  Google Scholar 

  38. Banerjee, M. R., Ganguly, N., Mehta, N. M., Iyer, A. P. and Ganguly, R. Functional differentiation and neoplastic transformation in an isolated whole mammary organ in vitro. In: Cell Biology of Breast Cancer (C. McGrath, M. Brennan and M. Rich, eds) Academic Press, NY, pp 485–516, 1980.

    Google Scholar 

  39. Nandi, S. Hormonal carcinogenesis: A novel hypothesis for the role of hormones. J. Environ. Pathol. Toxicol. 2: 13 – 20, 1978.

    PubMed  CAS  Google Scholar 

  40. Schaefer, F. V., Tonelli, Q. J., Dickens, M. S., Custer, R. P. and Sorof, S. Nononcogenic hormone-independent alveoli produced by carcinogens in cultured mouse mammary glands. Cancer Res. 43: 3310 – 3315, 1983.

    PubMed  CAS  Google Scholar 

  41. Dickens, M. S. and Sorof, S. Retinoid prevents transformation of cultured mammary glands but not by nonactivated procarcinogens. Nature 285: 581 – 584, 1980.

    Article  PubMed  CAS  Google Scholar 

  42. DeOme, K. B., Faulkin, L. T. Jr., Bern, H. A. and Blair, P. B. Development of mammary tumors from hyperplastic alveolar nodule transplanted into gland-free mammary fat pad of female C3H mice. Cancer Res. 19: 515 – 520, 1959.

    PubMed  CAS  Google Scholar 

  43. Telang, N. T., Banerjee, M. R., Iyer, A. P. and Kundu, A. B. Neoplastic transformation of epithelial cells in whole mammary gland in vitro. Proc. Natl. Acad. Sci. U.S.A. 76: 5886 – 5890, 1979.

    Article  PubMed  CAS  Google Scholar 

  44. Iyer, A. P. and Banerjee, M. R. Sequential expression of preneoplastic and neoplastic characteristics of mouse mammary epithelial cells transformed in organ culture. J. Nat. Cancer Inst. 66, 893 – 905, 1981.

    PubMed  CAS  Google Scholar 

  45. Mehta, R. G., Washburn, L. L., Young, P. N., Bern, H. A. and Banerjee, M. R. Brief communication: Proliferation of preneoplastic mammary nodule outgrowth in mammary fat pads of BALB/c mice in organ culture. J. Nat. Cancer Inst. 52: 1012 – 1015, 1974.

    Google Scholar 

  46. Ganguly, N., Ganguly, R., Mehta, N. M. and Banerjee, M. R. Growth and differentiation of hyperplastic outgrowths derived from mouse mammary epithelial cells transformed in organ culture. J. Nat. Cancer Inst. 69: 453 – 463, 1982.

    PubMed  CAS  Google Scholar 

  47. Pauley, R. J. and Socher, S. H. Hormonal influences on the expression of casein messenger RNA during mouse mammary tumorigenesis. Cancer Res. 40: 362 – 367, 1980.

    PubMed  CAS  Google Scholar 

  48. Moon, R. C., Grubbs, C. J. and Sporn, M. B. Inhibition of 7,12-dimethylbenz[a]anthracene-induced mammary carcinogenesis by retinyl acetate. Cancer Res. 36, 2626–2630

    Google Scholar 

  49. Sporn, M. B. and Roberts, A. B. The role of retinoids in differentiation and carcinogenesis. Cancer Res. 43: 3034 – 3040, 1983.

    PubMed  CAS  Google Scholar 

  50. Sporn, M. B., Newton, D. L., Smith, J. M., Acton, N., Jacobson, A. E. and Brossi, A. Retinoids and cancer prevention: the importance of the terminal group of the retinoid molecule in modifying activity and toxicity. In:Carcinogenesis: Identification and Mechanisms of Action (A. C. Griffin and C. R. Shaw, eds) Raven Press, NY. pp. 441–453, 1979.

    Google Scholar 

  51. Moon, R. C. and McCormick, D. L. Inhibition of chemical carcinogenesis by retinoids. J. Amer. Acad. Derm. 6, 809 – 814, 1982.

    Article  CAS  Google Scholar 

  52. Chatterjee, M. and Banerjee, M. R. Influence of hormones on N-(4-hydroxyphenyl)retinamide inhibition of 7,12-dimethylbenz(a)-anthracene transformation of mammary cells in organ culture. Cancer Lett. 16: 239 – 245, 1982.

    Article  PubMed  CAS  Google Scholar 

  53. McCormick, D. L., Mehta, R. G., Thompson, C. A., Dinger, N., Caldwell J. A. and Moon, R. C. Enhanced inhibition of mammary carcinogenesis by combined treatment with N-(4-hydroxyphenyl)-retinamide ovariectomy. Cancer Res. 42: 508 – 512, 1982.

    PubMed  CAS  Google Scholar 

  54. Welsch, C. W., Brown, C. K., Goodrich-Smith, M., Chiusano, J. and Moon, R. C. Synergistic effect of chronic prolactin suppression and retinoid treatment in the prophylaxis of N-methyl-N-nitroso-urea-induced mammary tumorigenesis in female Sprague-Dawley rats. Cancer Res. 40: 3095 – 3098, 1980.

    PubMed  CAS  Google Scholar 

  55. Griffin, A. C. Role of selenium in the chemoprevention of cancer. Adv. Cancer Res. 29: 419 – 442, 1979.

    Article  PubMed  CAS  Google Scholar 

  56. Griffin, A. C. The chemopreventive role of selenium in carcinogenesis. In:Molecular Interrelations of Nutrition and Cancer (M. S. Arnott, J. Van Eys and Y. M. Wang, eds) Raven Press, NY, pp. 401–408, 1982.

    Google Scholar 

  57. Medina, D. and Shepherd, F. Selenium mediated inhibition of mouse mammary tumorigenesis. Cancer Lett. 8, 241 – 245, 1980.

    Article  PubMed  CAS  Google Scholar 

  58. Medina, D. and Shepherd, F. Selenium mediated inhibition of 7,12-dimethylbenz(a)anthracene-induced mouse mammary tumorigenesis. Carcinogenesis 2: 451 – 455, 1981.

    Article  PubMed  CAS  Google Scholar 

  59. Medina, D., Lane, H. W. and Tracy, C. M. Selenium and mouse mammary tumorigenesis: an investigation of possible mechanisms. Cancer Res. 43: 2460 – 2404, 1983.

    CAS  Google Scholar 

  60. Medina, D., Lane, H. W. and Shepherd, F. Effect of dietary selenium levels on 7,12-dimethylbenz(a)anthracene-induced mouse mammary tumorigenesis. Carcinogenesis 4: 1159 – 1163, 1983.

    Article  PubMed  CAS  Google Scholar 

  61. Chatterjee, M. and Banerjee, M. R. Selenium mediated dose-dependent inhibition of 7,12-dimethylbenz[a]anthracene induced transformation of mammary cell in organ culture. Cancer Lett. 17: 187 – 195, 1982.

    Article  PubMed  CAS  Google Scholar 

  62. Medina, D. and Osborn, C. J. Differential effects of selenium on the growth of mouse mammary cells in vitro. Cancer Lett. 13: 333 – 344, 1981.

    Article  PubMed  CAS  Google Scholar 

  63. Peto, R., Doll, R., Buckley, J. D. and Sporn, M. B. Can dietary beta-carotene materially reduce human cancer rates? Nature 290: 201 – 208, 1981.

    Article  PubMed  CAS  Google Scholar 

  64. Epstein, J. H. Effects of beta-carotene on UV-induced cancer formation in the hairless mouse skin. Photochem. Photobiol. 25: 211 – 213, 1973.

    Article  Google Scholar 

  65. Mathews-Roth, M. M., Crean, C. and Clancy, M. The carotenoid content of various organs in animals administered large amounts of beta-carotene. Nutr. Rep. Int. 16: 419 – 423, 1977.

    CAS  Google Scholar 

  66. Mathews-Roth, M. M. Antitumor activity of beta-carotene, canthaxan-thin and phytoene. Oncology 39: 33 – 37, 1982.

    Article  PubMed  CAS  Google Scholar 

  67. Santamaria, L., Bianchi, A., Arnaboldi, A., Andreoni, L. and Bermond, P. Dietary carotenoids block photocarcinogenie enhancement by benzo(a)pyrene and inhibit its carcinogenesis in the dark. Experientia 39: 1043 – 1045, 1983.

    Article  PubMed  CAS  Google Scholar 

  68. Mathews-Roth, M. M. and Krinski, N. I. Effect of dietary fat levels on UV-B-induced skin tumor and antitumor action of beta-carotene. Photochem. Photobiol. 40: 671 – 673, 1984.

    Article  CAS  Google Scholar 

  69. Som, S., Chatterjee, M. and Banerjee, M. R. Beta-carotene inhibition of DMBA-induced transformation of murine mammary cells in vitro. Carcinogenesis 5: 937 – 940, 1984.

    Article  PubMed  CAS  Google Scholar 

  70. Kellogg (III), E. W. and Fridovich, I. Superoxide, hydrogen peroxide and singlet oxygen in lipid peroxidation by a xanthine oxidase system. J. Biol. Chem. 250: 8812 – 8817, 1975.

    PubMed  CAS  Google Scholar 

  71. Rana, R. S., Stevens, R. H., Oberley, L. W., Loven, D. P., Graves, J. M., Cole, D. A. and Meek, E. S. Evidence for a defective mitochondrial membrane in 1:2 diethylhydrazine induced colon adenocarcinoma in rat: Enhanced lipid peroxidation in vitro. Cancer Lett. 9: 237 – 246, 1980.

    Article  PubMed  CAS  Google Scholar 

  72. Popescu, N. C., Ansbaugh, S. C. and DiPaolo, J. A. Correlation of morphological transformation to sister chromatid exchanges induced by split doses of chemical or physical carcinogens on cultured syrian hamster cells. Cancer Res. 44: 1933 – 1938, 1984.

    PubMed  CAS  Google Scholar 

  73. Abe, S. and Sasaki, M. SCE as an index of mutagenesis/or carcinogenesis. In: Sister Chromatid Exchange (A. A. Sandberg, ed) Alan R. Liss, Inc., NY, pp 462–514, 1982.

    Google Scholar 

  74. Stock, A. D., Burnham, D. B. and Hsu, T. C. Giemsa binding of meiotic chromosomes with procedure for cytological preparation from solid tissue. Cytogenetics 11: 534 – 539, 1972.

    Article  PubMed  CAS  Google Scholar 

  75. Manoharan, K. and Banerjee, M. R. Measurements of chemical carcinogen-induced sister chromatid exchanges in a whole organ in vitro. Mutation Res. 147: 165 – 169, 1985.

    PubMed  CAS  Google Scholar 

  76. Manoharan, K. and Banerjee, M. R. Beta-carotene reduces sister chromatid exchanges induced by chemical carcinogens in mouse mammary cells in organ culture. Cell Biol. Intern’l Reports 9: 783 – 789, 1986.

    Article  Google Scholar 

  77. Foote, C. S. and Denney, R. W. Photosensitized oxidation and singlet oxygen: Consequence in biological system. J. Am. Chem. Soc. 90: 6233 – 6235, 1968.

    Article  CAS  Google Scholar 

  78. Burton, G. W. and Ingold, K. V. Beta-carotene: An unusual type of lipid antioxidant. Science 224: 569 – 573, 1984.

    Article  PubMed  CAS  Google Scholar 

  79. Heidelberger, C. Chemical carcinogenesis in culture. Adv. Cancer Res. 18: 317 – 3666, 1973.

    Article  PubMed  CAS  Google Scholar 

  80. Miller, J. A. and Miller, E. C. Search for ultimate chemical carcinogens and their reactions with cellular macromolecules. In:Accomplishment in Cancer Research (Froter and Rhodes, eds), pp. 63–98, 1980.

    Google Scholar 

  81. Thompson, H. J., Meeker, L. D., Becci, P. J. and Kokoska, S. Effect of short-term feeding of sodium selenite on 7,12-dimethylbenz(a)-anthracene-induced mammary carcinogenesis in the rat. Cancer Res. 42: 4954 – 4958, 1982.

    PubMed  CAS  Google Scholar 

  82. Thompson, H. J., Meeker, L. D. and Kokoska, S. Effect of an inorganic and organic form of dietary selenium on the promotional stage of mammary carcinogenesis in the rat. Cancer Res. 44: 2803 – 2806, 1984.

    PubMed  CAS  Google Scholar 

  83. Thompson, H. J. Selenium as an anticarcinogen. J. Agric. Food Chem. 32: 422 – 425, 1984.

    Article  CAS  Google Scholar 

  84. Ip, C. and Danial, F. B. Effects of selenium on 7,12-dimethylbenz-(a)anthracene-induced mammary carcinogenesis and DNA adduct formation. Cancer Res. 45: 610 – 65, 1985.

    Google Scholar 

  85. Bigger, C. A. H., Tomaszewski, J. E., Dipple, A. and Lake, R. S. Limitations of metabolic activation systems used with in vitrotests for carcinogens. Science 209: 503 – 505, 1980.

    Article  PubMed  CAS  Google Scholar 

  86. Milner, J. A., Pigott, M. A. and Dipple, A. Selective effects of selenium selenite on 7,12-dimethylbenz(a)anthracene-DNA binding in fetal mouse cell cultures. Cancer Res. 45: 6347 – 6354, 1985.

    PubMed  CAS  Google Scholar 

  87. Banerjee, M. R., Kinder, D. L. and Wagner, J. E. Binding patterns of 3-methylcholanthrene to replicating and nonreplicating DNA of preneoplastic nodule of mouse mammary gland. Cancer Res. 33: 862 – 866, 1973.

    PubMed  CAS  Google Scholar 

  88. Kundu, A. B., Telang, N. T. and Banerjee, M. R. The binding of 7,12-dimethylbenz(a)anthracene to mammary cell DNA in organ culture. J. Nat. Cancer Inst. 61: 465–469

    Google Scholar 

  89. Janss, D. H., Moon, R. C. and Irving, C. C. The binding of 7,12-dimethylbenz(a)anthracene to mammary parenchyma DNA and protein in vivo. Cancer Res. 32: 254 – 258, 1972.

    PubMed  CAS  Google Scholar 

  90. Lin, S. S. and Dao, T. L. Binding of polycyclic hydrocarbon to rat mammary gland cellular macromolecules. Proc. Soc. Exp. Biol. Med. 138: 814 – 816, 1971.

    PubMed  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Tumor Biology Laboratory School of Biological Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska, 68588-0342, USA

    Mihir R. Banerjee, Sarbani Chakraborty & Denva Kinder

  2. Department of Radiology and Pharmacology, Duke University Medical Center, Durham, NC, 27710, USA

    Kaliamoorthy Manoharan

  3. Department of Molecular Cell and Developmental Biology, University of Colorado-Boulder, Boulder, Colorado, 80309, USA

    Ravi Menon

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  1. Mihir R. Banerjee
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  2. Sarbani Chakraborty
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  3. Denva Kinder
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  4. Kaliamoorthy Manoharan
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Editors and Affiliations

  1. Baylor College of Medicine, Houston, Texas, USA

    Daniel Medina

  2. National Cancer Institute, Bethesda, Maryland, USA

    William Kidwell  & Elizabeth Anderson  & 

  3. Michigan Cancer Foundation, Detroit, Michigan, USA

    Gloria Heppner

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© 1987 Plenum Press, New York

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Banerjee, M.R., Chakraborty, S., Kinder, D., Manoharan, K., Menon, R. (1987). Cell Biology of Mouse Mammary Carcinogenesis in Organ Culture. In: Medina, D., Kidwell, W., Heppner, G., Anderson, E. (eds) Cellular and Molecular Biology of Mammary Cancer. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0943-7_20

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  • DOI: https://doi.org/10.1007/978-1-4613-0943-7_20

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