Abstract
The development of the mouse mammary gland starts during fetal life around day 10 to 11 after fertilization (Fig. 1). By day 13, the epidermis shows focal outgrowths or invaginations into the underlying mesenchymal structures. In a few days, these foci of epithelial growth show a centerally located lumen and the earliest development of a duct. The basic design of the mammary gland is finished by day 17 of embryonal life (1,2). The second important phase in development begins around the 4th week of life in female mice. A system of branching ducts develops in the fat pads. The tip of the ducts show club-shaped structures, called endbuds.
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© 1987 Plenum Press, New York
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Daams, J., Sonnenberg, A., Sakakura, T., Hilgers, J. (1987). Changes in Antigen Patterns During Development of the Mouse Mammary Gland: Implications for Tumorigenesis. In: Medina, D., Kidwell, W., Heppner, G., Anderson, E. (eds) Cellular and Molecular Biology of Mammary Cancer. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0943-7_1
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DOI: https://doi.org/10.1007/978-1-4613-0943-7_1
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