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Developmental-Behavioral Disorders pp 313–321Cite as

Neurologic Aspects of Autism and Rett Syndrome

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Abstract

Autism is a rare disorder (2–4 cases per 10,000) but a serious one. The diagnosis of autism remains a clinical one. The criteria for diagnosis are not uniformly agreed upon and there is no one pathognomonic clinical feature. Thus, the situation is rather like that for Tourette disease or, for that matter, common migraine. Nonetheless, there are certain features without which the diagnosis should not be made, namely, it is a disorder that affects multiple brain-related functions and abnormalities are present on examination that are not normal for any stage of development. There is a distortion, not merely a delay, in development.

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References

  • Clancy, H., Dugdale, A., and Rendle-Short, J., 1969, The diagnosis of infantile autism, Dev. Med. Child Neurol 11:432–442.

    Article  PubMed  CAS  Google Scholar 

  • Hagberg, B., Aicardi, J., Dias, K., et al. , 1983, A progressive syndrome of autism, dementia, and loss of purposeful hand use in girls: Rett’s syndrome: report of 35 cases, Ann. Neurol 14:471–479.

    Article  PubMed  CAS  Google Scholar 

  • Kanner, L., 1943, Autistic disturbances of affective contact, The Nervous Child 2:217–250.

    Google Scholar 

Suggested Reading: Autism

  • American Psychiatric Association, 1980, Pervasive developmental disorders, in: Diagnostic and Statistical Manual of Mental Disorders, ed. 3, 1980, pp. 86–92, American Psychiatric Association, Washington, D.C.

    Google Scholar 

  • Brauman, M., and Kemper, T.L., 1985, Histoanatomic observations of the brain in early infantile autism, Neurology 35:866–874.

    Google Scholar 

  • Cantwell, D. P., 1986 Is autism a treatable disorder? Internal. Pediatr. l:(suppl. l):48-50.

    Google Scholar 

  • Damasio, A.R., and Maurer, R.G., 1978, A neurologic model for childhood autism, Arch. Neurol 35:777–786.

    PubMed  CAS  Google Scholar 

  • Demasio, H., Maurer, R. G., Demasio, A. R., et al. , 1980, Computerized tomographic scan findings in patients with autistic behavior, Arch. Neurol 37:504–510.

    Google Scholar 

  • Darby, J.K., 1976, Neuropathologic aspects of psychosis in children, J. Autism Childh. Schiz. 6:339–352.

    Article  CAS  Google Scholar 

  • DeMyer, W., and DeMyer, M., 1984, Infantile autism, Neurol Clin. 2:139–152.

    PubMed  CAS  Google Scholar 

  • Hauser, S.L., DeLong, G.R., and Rosman, N.P., 1975, Pneumographic findings in the infantile autism syndrome. A correlation with temporal lobe disease, Brain 98:667–688.

    CAS  Google Scholar 

  • Herskowitz, J., and Rosman, N. P., 1982, Autism, schizophrenia and other psychoses, in: Pediatrics, Neurology and Psychiatry—Common Ground: Behavioral, cognitive, affective and physical disorders in childhood and adolescence, pp. 65–110, Macmillan, New York.

    Google Scholar 

  • Kanner, L., 1971, Follow-up study of eleven autistic children originally reported in 1943, J. Autism Childh. Schiz. 1:119–145.

    Article  CAS  Google Scholar 

  • Michels, V.V., 1985, Fragile sites on human chromosomes, description and clinical significance, Mayo Clin. Proc. 60:690–696.

    PubMed  CAS  Google Scholar 

  • Ritvo, E.R., Freeman, B.J., Yuwiler, A., et al. , 1984, Study of fenfluramine in outpatients with the syndrome of autism, J. Pediatr. 105:823–828.

    Article  PubMed  CAS  Google Scholar 

  • Ritvo, E. R., Freeman, B. J., Geller, E., et al. , 1983, Effects of fenfluramine on 14 outpatients with the syndrome of autism, J. Am. Acad. Child Psychol 22:549–558.

    Article  CAS  Google Scholar 

  • Rutter, M., and Hersov, L., 1985, Infantile autism and other pervasive developmental disorders, in: Child and Adolescent Psychiatry: Modern approaches, ed. 2, pp. 545–566, Blackwell Scientific, Oxford.

    Google Scholar 

  • Stubbs, E.G., Budden, S.S., Jackson, R.H., et al. , 1986, Effects of fenfluramine on eight outpatients with the syndrome of autism, Dev. Med. Child. Neurol 28:229–235.

    Article  PubMed  CAS  Google Scholar 

  • Al-Mateen, M., Philippart, M., and Shields, W.D., 1986, Rett syndrome, a commonly overlooked progressive encephalopathy in girls. Am. J. Dis. Child. 140:761–765.

    PubMed  CAS  Google Scholar 

  • Kerr, A.M., and Stephenson, J.B.P., 1985, Rett’s syndrome in the west of Scotland, Brit. Med. J. 291:579–582.

    Article  CAS  Google Scholar 

  • Rett, A., 1977, Cerebral atrophy associated with hyperammonaemia, in: Handbook of Clinical Neurology, vol. 29, (P.J. Vinken, and G.W. Bruyn, eds), pp. 305–329, North-Holland, Amsterdam.

    Google Scholar 

  • Rett, A., Fukuyama, Y., and Hagberg, B. (eds.), 1985, Proceedings of the September 1984 Vienna Symposium on Rett syndrome, Brain and Develop. 7(3):271-374.

    Google Scholar 

  • Opitz, J. M. (ed.), 1986, Proceedings of the Second International Conference on Rett Syndrome, Am. J. Med. Genet. 24(suppl 1): 1-404.

    Google Scholar 

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Authors and Affiliations

  1. Departments of Pediatrics and Neurology, Tufts University School of Medicine, and Division of Pediatric Neurology, Floating Hospital for Infants and Children, New England Medical Center Hospitals, Boston, Massachusetts, 02111, USA

    N. Paul Rosman

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  1. N. Paul Rosman
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Editor information

Editors and Affiliations

  1. Section of Developmental Pediatrics, Hackensack Medical Center, Hackensack, New Jersey, USA

    John E. Williams M.D. (Chief, Associate Director, Clinical Assistant Professor) (Chief, Associate Director, Clinical Assistant Professor)

  2. Department of Pediatrics, University of Medicine and Dentistry of New Jersey-New Jersey Medical School, Newark, New Jersey, USA

    Marvin I. Gottlieb M.D., Ph.D. (Director, Professor) & John E. Williams M.D. (Chief, Associate Director, Clinical Assistant Professor) (Director, Professor) &  (Chief, Associate Director, Clinical Assistant Professor)

  3. Institute for Child Development, Hackensack Medical Center, Hackensack, New Jersey, USA

    Marvin I. Gottlieb M.D., Ph.D. (Director, Professor) & John E. Williams M.D. (Chief, Associate Director, Clinical Assistant Professor) (Director, Professor) &  (Chief, Associate Director, Clinical Assistant Professor)

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© 1988 Plenum Publishing Corporation

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Rosman, N.P. (1988). Neurologic Aspects of Autism and Rett Syndrome. In: Gottlieb, M.I., Williams, J.E. (eds) Developmental-Behavioral Disorders. Critical Issues in Developmental and Behavioral Pediatrics. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0939-0_20

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  • DOI: https://doi.org/10.1007/978-1-4613-0939-0_20

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8255-6

  • Online ISBN: 978-1-4613-0939-0

  • eBook Packages: Springer Book Archive

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