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The Heterogeneity of the Catecholamine Innervation of Cerebral Cortex

Biochemical and Electrophysiological Studies

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Neurotransmitters and Cortical Function

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Abstract

The central catecholamine (CA) neurons in the brain stem and their CNS projections were the first to be described in correlative biochemical and histofluorescent investigations as chemically identified neurotransmitter systems. By combining histofluorescent, autoradiographic, and immunocytochemical methods with biochemical determinations of endogenous levels and activities of the enzymes of synthesis, three types of CA neuronal systems were described in the CNS, according to the monoamine they can synthesize and presumably use as their neurotransmitter, i.e., dopamine (DA; Berger et al, 1974; Hökfelt et al, 1974; Lindvall et al, 1974), noradrenaline (NA; Carlsson et al., 1962; Dahlström and Fuxe, 1964; Fuxe, 1965; Fuxe et al., 1968; Ungerstedt, 1971; Lindvall and Björklund, 1974), and adrenaline (AD; Hökfelt et al, 1973; Van der Gugten et al, 1976; Versteeg et al, 1976; Reader, 1981).

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Authors
  1. Tomás A. Reader
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  2. André Ferron
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  3. Laurent Diop
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  4. Arlette Kolta
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  5. Richard Brière
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Editor information

Editors and Affiliations

  1. McGill University and Montreal Neurological Institute, Montreal, Quebec, Canada

    Massimo Avoli  & Pierre Gloor  & 

  2. University of Montreal, Montreal, Quebec, Canada

    Tomás A. Reader

  3. McGill University and Royal Victoria Hospital, Montreal, Quebec, Canada

    Robert W. Dykes

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© 1988 Plenum Press, New York

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Reader, T.A., Ferron, A., Diop, L., Kolta, A., Brière, R. (1988). The Heterogeneity of the Catecholamine Innervation of Cerebral Cortex. In: Avoli, M., Reader, T.A., Dykes, R.W., Gloor, P. (eds) Neurotransmitters and Cortical Function. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0925-3_22

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  • DOI: https://doi.org/10.1007/978-1-4613-0925-3_22

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8248-8

  • Online ISBN: 978-1-4613-0925-3

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