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Oxygen, Free Radicals, Shock and Trauma

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Lipid Mediators in the Immunology of Shock

Part of the book series: NATO ASI Series ((NSSA,volume 139))

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Abstract

In atoms and molecules, the electrons generate, by rotation, a magnetic field represented by a vector, the spin. Generally, all the electrons are paired, opposing their spins, the resulting magnetic field being null. In molecules, electrons of neighbouring atoms are paired, forming covalent bonds, which can be broken by a sufficient amount of energy; after this rupture, two electrons become unpaired and the implicated atoms or molecules acquire a magnetic field (Fig. 1). The energy can be furnished by radiations (UV, ionizing radiations) and by chemical or enzymatic reactions. Such atoms or molecules presenting an odd number of electrons, and thus a magnetic field, are called free radicals.

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References

  1. Pryor WA. in: Introduction to free radical chemistry. Prentice-Hall, Inc., Englewood Cliffs (New-Jersey) (1966).

    Google Scholar 

  2. Hill HAO. in: Oxygen free radicals and tissue damages. Ciba Found. Symp. 65. Excerpta Medica, p 5 (1979).

    Google Scholar 

  3. Buege JA, and Aust SD. Methods Enzymol. 51: 302 (1978).

    Article  Google Scholar 

  4. Hamilton GA. in: Molecular mechanisms of oxygen activation (ed; O. Hayashi). Academic Press (New-York) p 405 (1974).

    Google Scholar 

  5. Del Maestro RF, Thaw HH, Bjork J, and Arfors KE. Acta Physiol Scand, suppl. 492: 43 (1980).

    Google Scholar 

  6. Sugioka K, Nakano H, Tero-Kubota S, and Ikegani Y. Biochem Biophys Acta, 753: 411 (1983).

    PubMed  CAS  Google Scholar 

  7. Porter NA. Methods Enzymol, 105: 273 (1984).

    Article  PubMed  CAS  Google Scholar 

  8. Boveris A, Turrens JF. in: Chemical and biochemical aspects of superoxide and superoxide dismutase (eds: J.V. Bannister and H.A.O Hill). Elsevier/North-Holland (New-York) p 84 (1980).

    Google Scholar 

  9. McCord JM. New Engl J Med, 312: 159 (1985).

    Article  PubMed  CAS  Google Scholar 

  10. Roy RS, and McCord JM. Fed Proc, 41: 767 (1982).

    Google Scholar 

  11. White BC, Krause GS, Aust SD, and Eyster GE. Ann Emerg Med, 14: 804 (1985).

    Article  PubMed  CAS  Google Scholar 

  12. Deby C, Pincemail J, Hans P, Braquet P, Lion Y, Deby-Dupont G, and Goutier R. in: Cerebral Ischemia(eds: E. Bes, P. Braquet, R. Paoletti and B.K. Sjesjo). Excerpta Medica (Amsterdam, New York, Oxford) p 249 (1984).

    Google Scholar 

  13. McCay PB, Noguchi T, Fong KL, Lai EK, and Poyer JL. in: Free radicals in biology, vol. IV. Academic Press (New-York) p 155 (1980).

    Google Scholar 

  14. Doroshow JH, Locker GY, and Myers CE. J Clin Invest, 65: 128 (1980).

    Article  PubMed  CAS  Google Scholar 

  15. Henrici-Olive G, and 01ive S, in: Coordination and catalysis. Verlag Chemie (Weinheim, New-York) (1977).

    Google Scholar 

  16. Aust SD, White BC. Adv Free Radical Biol Med, 1: 1 (1985).

    Article  CAS  Google Scholar 

  17. Crichton RR. in: Ciba Found, Svmp. 65. Excerpta Medica. p 57 (1979).

    Google Scholar 

  18. Badwey JA, and Karnovski ML. Annu Rev Biochem, 49: 695 (1980).

    Article  PubMed  CAS  Google Scholar 

  19. Hammerschmidt DE, Harris PD, Wayland H, Craddock PR, and Jacob HS. Am J Pathol, 102: 146 (1981).

    PubMed  CAS  Google Scholar 

  20. Root RK, and Metcalf JA. J Clin Invest, 60: 1266 (1977).

    Article  PubMed  CAS  Google Scholar 

  21. Babior BM, Kipnes RS, Curnutte JT. J Clin Invest, 52: 741 (1973).

    Article  PubMed  CAS  Google Scholar 

  22. Grisham MB, Jefferson MM, Melton DF, and Thomas EL. J Biol Chem, 259 : 10404 (1984).

    PubMed  CAS  Google Scholar 

  23. Weiss SJ, Lampert MB, and Test ST. Science, 222: 625 (1983).

    Article  PubMed  CAS  Google Scholar 

  24. Freeman BA, and Tanswell AK. Adv Free Radical Biol Med, 1: 133 (1985).

    Article  CAS  Google Scholar 

  25. Deby-Dupont G, Hass M, Pincemail J, Braun M, Lamy M, Deby C, and Franchimont P. Intensive Care Med, 10: 7 (1984).

    Article  PubMed  CAS  Google Scholar 

  26. Deby C, Deby-Dupont G, Hans P, Pincemail J, and Neuray J. Experientia, 39: 1113 (1983).

    Article  CAS  Google Scholar 

  27. Bertrand Y, Artoisenet A, Allard B, Barbier B, de Meulder A, Raymaert M, Mathieu P, and Dumont E. Intensive Care Med, 11: 65 (1985).

    PubMed  CAS  Google Scholar 

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© 1987 Plenum Press, New York

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Deby, C., Lamy, M., Braquet, P., Goutier, R. (1987). Oxygen, Free Radicals, Shock and Trauma. In: Paubert-Braquet, M., Braquet, P., Demling, B., Fletcher, J.R., Foegh, M. (eds) Lipid Mediators in the Immunology of Shock. NATO ASI Series, vol 139. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0919-2_8

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  • DOI: https://doi.org/10.1007/978-1-4613-0919-2_8

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8245-7

  • Online ISBN: 978-1-4613-0919-2

  • eBook Packages: Springer Book Archive

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