Lipid Metabolism during Starvation and Sepsis in Relation to Fatty Acid Profile in Liver and α-Linolenic- and γ-Linolenic Acid-Enriched Diets

Larsson-Backström, C.; Paprocki, J.; Lindmark, L.; Svensson, L.

doi:10.1007/978-1-4613-0919-2_13

C. Larsson-Backström⁶,
J. Paprocki⁶,
L. Lindmark⁶ &
…
L. Svensson⁶

Part of the book series: NATO ASI Series ((NSSA,volume 139))

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Abstract

Starvation and sepsis induce metabolic changes of particular importance for the liver function. During sepsis, a condition characterized by starvation during the first, most severe period, the starvation induced ketonemia is markedly reduced (Flatt and Blackburn, 1974). Ketogenesis is assumed to be reduced by an inhibitory effect of malonyl-CoA (McGarry et al., 1978). Decreased responses to this inhibition have been reported in starvation (McGarry and Foster, 1979) and by long-chain fatty-acyl-CoA (Mills et al., 1983) in isolated mitochondria. The role of essential fatty acids (EFA) in liver lipids in these conditions is uncertain.

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Authors and Affiliations

Departments of Pharmacology and Nutrition, KabiVitrum AB, S-112 87, Stockholm, Sweden
C. Larsson-Backström, J. Paprocki, L. Lindmark & L. Svensson

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C. Larsson-Backström
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J. Paprocki
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L. Lindmark
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L. Svensson
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Editors and Affiliations

Centre de Traitement des Brules, Hopital d’Instruction des Armees Percy, Clamart, France
M. Paubert-Braquet
Institut Henri Beaufour, Le Plessis-Robinson, France
P. Braquet
Longwood Area Trauma Center, Harvard Medical School, Boston, Massachusetts, USA
B. Demling
St. Thomas Hospital, Nashville, Tennessee, USA
J. R. Fletcher
Georgetown University Medical Center, Washington, D.C., USA
M. Foegh

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Larsson-Backström, C., Paprocki, J., Lindmark, L., Svensson, L. (1987). Lipid Metabolism during Starvation and Sepsis in Relation to Fatty Acid Profile in Liver and α-Linolenic- and γ-Linolenic Acid-Enriched Diets. In: Paubert-Braquet, M., Braquet, P., Demling, B., Fletcher, J.R., Foegh, M. (eds) Lipid Mediators in the Immunology of Shock. NATO ASI Series, vol 139. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0919-2_13

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DOI: https://doi.org/10.1007/978-1-4613-0919-2_13
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4612-8245-7
Online ISBN: 978-1-4613-0919-2
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