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Control of the Coronary Circulation

  • Harvey V. SparksJr
  • Roger D. Wangler
  • Mark W. Gorman
Part of the Developments in Cardiovascular Medicine book series (DICM, volume 90)

Abstract

Normal function of the heart depends on an adequate coronary blood flow. Myocardial metabolism and coronary flow are mutually interactive so that any increase in the metabolism of the normal heart is matched by an increase in coronary blood flow, and any significant restriction of flow results in the reduction of myocardial metabolism and cardiac performance.In this chapter we discuss the determinants of coronary blood flow, which include myocardial metabolism, humoral influences, and neural control.We will not discuss the role of physical factors in determining coronary blood flow because that is the subject of the chapter by Dr. Downey.In adddtion, we discuss certain pathophysiologic conditions, such as vascular responses to cardiac hypertrophy and myocardial ischemia, and the significance of coronary collateral vessels.

Keywords

Left Ventricular Hypertrophy Cardiac Hypertrophy Myocardial Blood Flow Coronary Blood Flow Adenosine Deaminase 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Kluwer Academic Publishers 1989

Authors and Affiliations

  • Harvey V. SparksJr
  • Roger D. Wangler
  • Mark W. Gorman

There are no affiliations available

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