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Systemic therapy with single agents for advanced or recurrent endometrial carcinoma

  • Tate Thigpen
Part of the Cancer Treatment and Reasearch book series (CTAR, volume 49)

Abstract

Endometrial carcinoma, now the most common invasive lesion of the female genital tract with over 40,000 cases annually, is regarded as a curable malignancy for several reasons: (1) symptoms in the form of abnormal bleeding occur early in the disease course, (2) the process at diagnosis is usually confined to the corpus of the uterus, (3) a majority of such lesions are well differentiated, and (4) the resultant cure rate from surgery alone is better than 90%. Despite this evidence of success, overall survival figures show that one-third of all patients with endometrial carcinoma recur within five years of diagnosis; most of these die from the malignancy. Until thirteen years ago, no major effort had sought effective systemic therapy for these unfortunate individuals.

Keywords

Endometrial Cancer Clin Oncol Endometrial Carcinoma Medroxyprogesterone Acetate Marginal Activity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Kluwer Academic Publishers 1989

Authors and Affiliations

  • Tate Thigpen

There are no affiliations available

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