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Clinical Aspects of Hemodialysis Biocompatibility

  • Alfred K. Cheung
Part of the Developments in Nephrology book series (DINE, volume 24)

Abstract

Bioincompatibility of the hemodialysis extracorporeal circuit occurs primarily through one of several mechanisms: (a) cell adhesion, aggregation and activation; (b) transformation and adsorption of noncellular elements such as proteins; (c) mechanical shear; and (d) leaching and spallation of substances (1). Many substances are produced in the hemodialysis circuit which have theoretical biological effects. Whether these substances in fact lead to the theoretical effects, however, depend on a number of other factors: the timing and location of the production of the substances as well as the thresholds for the potential consequential events.

Keywords

Dialysis Patient Hemodialysis Patient Complement Activation Ethylene Oxide Cellulosic Dialysis Membrane 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Kluwer Academic Publishers 1989

Authors and Affiliations

  • Alfred K. Cheung
    • 1
    • 2
  1. 1.Renal SectionVeterans Administration Medical CenterSalt Lake CityUSA
  2. 2.The Department of MedicineUniversity of Utah School of MedicineSalt Lake CityUSA

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