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Intradialytic Behaviour of β-2-Microglobulin During Acetate Dialysis (HDac), Biofiltration (BF) and Paired Filtration Dialysis (PFD)

  • V. Savica
  • G. Bellinghieri
  • A. Mallamace
  • B. Ricciardi
  • F. Torre
  • A. Saporita
  • C. Giardina
  • M. L. Resta
  • M. Egitto
  • G. Cavallaro
Part of the Developments in Nephrology book series (DINE, volume 24)

Abstract

Literature data report the presence of a like-amyloid substance in the tendons, synovias and in the bones of the patients undergoing long term dialytic treatment (1,2,3,4). The β-2-microglobulin, produced by lynphoid cells and by the mastocytes when the blood comes into contact with the dialytic membranes, was identified as the most important component of the like-amyloid substance. Many autors (1,2,3,4) refer that the above substance plays a negative role on the bones allegation progression of the dialyzed patients and it may be considered as an index of the adequate dialysis. The above considerations and the introduction of the PFD among the new dialytic strategies, suggested us to carry a study on the intradialytic behaviour of β-2-microglobulin during standard haemodialytic treatment using cuprophan membranes during BF and during PFD using respectively AN 69 S and Cuprophan associated to Polisulphone membranes.

Keywords

Dialyze Patient Dialytic Membrane Dialytic Treatment Nephrol Dial Transplant Adequate Dialysis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Kluwer Academic Publishers 1989

Authors and Affiliations

  • V. Savica
    • 1
  • G. Bellinghieri
    • 2
  • A. Mallamace
    • 3
  • B. Ricciardi
    • 3
  • F. Torre
    • 3
  • A. Saporita
    • 3
  • C. Giardina
    • 3
  • M. L. Resta
    • 3
  • M. Egitto
    • 3
  • G. Cavallaro
    • 4
  1. 1.Cattedre di Nefrologia SperimentaleUniversità di MessinaItaly
  2. 2.NefrologiaUniversità di MessinaItaly
  3. 3.Clinica Medica 1Università di MessinaItaly
  4. 4.Clinica ChirurgicaUniversità di MessinaItaly

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